Title: Study of Cystatin C as a Risk Factor for Myocardial Infarction in Patients with Normal Renal Function
Authors: Dr G. Arul Venkadesh, Prof. Dr M.Senthilvelan, Dr K. Baburaj, Dr A. Elaiyaraja, Dr Jayaram Kosalram, Dr G.Sivachandran
DOI: https://dx.doi.org/10.18535/jmscr/v6i10.166
Abstract
Objective and Design: Cystatin C facilitates the progression of atherosclerosis by regulating inflammation and thereby it has a significant impact on pathogenesis of Myocardial Infarction. In this study we assessed the association between cystatin C and Myocardial Infarction in a consecutive series of patients with normal kidney function.
Materials and Methods: 40 Patients of age 30 to 60 years of both sexes, attending casualty within 12hours after the onset of symptoms in Rajah Muthiah Medical college and hospital, Annamalai University during the period of November 2016 till August 2018, diagnosed as Acute Myocardial Infarction with normal renal function, normal thyroid function without any malignancies / recent surgeries were taken for present study.
Results: Cystatin C was elevated among 82.5% of the total patients participated in the study. Cystatin C being less influenced by age, gender, and muscle mass and can be considered as a better indicator of cardiovascular risk especially Myocardial Infarction. CYSTATIN C to be considered as an independent risk factor for Acute Myocardial Infarction in patients with normal renal function.
Keywords: Acute Myocardial infarction, STEMI, NSTEMI, CYSTATIN C.
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