Title: Maternal Hyperuricemia and Birth Outcome in Normotensive Singleton Pregnancy: A Prospective Cohort Study
Authors: Dr Tahmina Afreen Daise, Prof. Dr Saria Tasnim, Prof. Dr Nahid Yasmin, Dr AKM Badrul Ahsan, Prof. Dr Wahida Khanam, Dr Mozibur Rahman
DOI: https://dx.doi.org/10.18535/jmscr/v6i10.160
Abstract
Introduction: Hyperuricemia is a common finding in preeclamptic pregnancies evident from early pregnancy.
Objective: In this study our main goal is to evaluate the effect of maternal hyperuricemia and birth outcome in normotensive singleton pregnancy.
Method: This prospective study was conducted at the department of Obstetrics and Gynecology, Institute of Child and Mother Health, Dhaka from January 2016 to January 2017 where total 102 normotensive singleton pregnant women examined. Two patients were excluded from the study due to lack of data. Data were analyzed using SPSS -21 windows version statistical package. Categorical variables were presented by frequency and percentage, and continuous variable by mean (sd) in case of normally distributed data and median (min-Max) in case of asymmetric data.
Results: During the study SBP mean level was 35.66 higher than DBP and for pregnant women found that gestational age 38 weeks and over then the serum uric acid level was higher. Also, LBWB was 36.7% lower than hyperuricemia.
Conclusion: we can conclude that Hyperuricemia is a risk factor for adverse pregnancy outcome for normotensive mother and LBWB is a concern in this regard. More studies and examinations are needed to confirm these results, as genetic, socioeconomic and dietary factors play key roles in uric acid concentrations.
Keywords: Hyperuricemia, Normotensive, Low birth weight baby (LBWB).
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