Abstract
Gastrointestinal stromal tumour (GIST) is a rare tumour of GI tract (0.2%). GIST arise from Interstitial cell of Cajal which intercalates between smooth muscle cells and intramural neuron. Stomach is the most common site followed by small bowel, rectum and colon. Commonly presents as abdominal pain, GI bleed, Intestinal obstruction and perforation. In spite of the impressive advances in the diagnosis and target therapy for GIST, surgery remains the standard treatment. We report a case of GIST originating from stomach in a 53 year male who presented with the mass abdomen and weight loss with emphasis on its going through surgical resection in our Institute.
Keywords: GIST, Stomach, GIANT.
References
- Miettinen M, Furlong M, Sarlomo-Rikala M, Burke A, Sobin LH, Lasota J. Gastrointestinal stromal tumors, intramural leiomyomas and leiomyosarcomas in the rectum and anus: a clinicopathologic histochemical and molecular genetic study of 144 cases. Am J Surg Path 2001; 25(9):1121-1133
- Miettinen M, Sarlomo-Rikala M, Lasota J. Gastrointestinal stromal tumors: recent advances in understandingof their biology. Hum Pathol 1999; 30: 1213-1220.
- Gokhale U, Pillai GR. Large Brunner’s Gland Hamartoma: A Case Report. Oman Med J 2009 Jan;24(1):41-43
- Miettinen M, El-Rifai W, Sobin LH, Lasota J: Evaluation of malignancy andprognosis of gastrointestinal stromal tumors: a review. Hum Pathol 2002; 33: 478-483
- DeMatteo RP, Lewis JJ, Leung D, Mudan SS, Woodruff JM, BrennanMF. Two hundred gastrointestinal stromal tumors: recurrence patterns and prognostic factors for survival. Ann Surg. 2000; 231:51–58
- Fletcher CD, Berman JJ, Corless C, Gorstein F, Lasota J, Longley BJ, et al. Diagnosis of gastrointestinal stromal tumors: A consensus approach. Hum Pathol 2002. May;33(5):459-465 10.1053/hupa.2002.123545.
- Das A., Wilson R., Biankin A.V., Merrett N.D. Surgical therapy for gastrointestinal stromal tumours of the upper gastrointestinal tract. J. Gastrointest. Surg. 2009;13:1220–1225.
- Pidhorecky I, Cheney RT, Kraybill WG, Gibbs JF: Gastrointestinal stromal tumors: current diagnosis, biologic behavior, and management. Ann SurgOncol 2000; 7(9): 705-712.
Corresponding Author
R.N. Guru
Email: This email address is being protected from spambots. You need JavaScript enabled to view it., Mob no-8328963343
DOI: https://dx.doi.org/10.18535/jmscr/v6i10.109
