Abstract
Background: Both of Type 2 diabetes mellitus and depression are major public health problems. Diabetes mellitus is characterized by increased level of blood glucose, its prevalence is increasing globally. Depression is a psychological disorder that affects large number of population worldwide. Association between depression and type 2 diabetes mellitus was reported.
Aim: To define the prevalence of depression and its associated risk factors among adult patients with type 2 diabetes.
Method: This study is cross sectional single centre study, it was conducted on patients with type2 diabetes at primary care center, Security Forces Hospital, Riyadh Saudi Arabia. The study was performed between the period from 1st of May 2017 to 1st of Jun 2017, using validated questionnaire. Statistical analysis and possible correlations were performed.
Results: Depression was prevalent in 55% of Type2 Diabetes Mellitus patients, with more prevalence of simple depression (26.2%). Different factors were associated with the prevalence of depression including personal characteristics such as age (P-value=0.005), gender (P-value=0.005), educational level (P-value=0.006) and monthly income (P-value=0.0001) as well as clinical characteristics such as time of diagnosis (P-value=0.023) and presence of chronic diseases (P-value=0.027).
Conclusion: Depression was moderately prevalent among type 2 diabetic patients with more prevalence of simple depression. Age, gender, educational level, salary, time of disease diagnosis, and presence of chronic diseases were associated with depression prevalence.
Keywords: Depression prevalence, Type 2 diabetes, depression, Saudi Arabia.
References
- Mirghani HO, Mohammed OS, Saadallah AM. Prevalence of depression among Sudanese patients with type-2 diabetes mellitus. Prevalence. 2014; 1;9(3).
- International Diabetes Federation. Diabetes Atlas, 4th edition. 2009. Available from: http://www.worlddiabetesfoundation.org/co mposite-35.htm. [cited 2015 Jan].
- Al-Rubeaan K, Al-Manaa HA, Khoja TA, Ahmad NA, Al-Sharqawi AH, Siddiqui K, et al. Epidemiology of abnormal glucose metabolism in a country facing its epidemic: SAUDI-DM study. J Diabetes. 2014 Sep 30.
- Global report on diabetes executive summary [Internet]. Available from: http://apps.who.int/iris/bitstream/10665/ 204871/1/9789241565257_eng.pdf.
- International diabetes federation. IDF Diabetes Atlas. Brussels, Belgium: International diabetes federation, 2011.
- Thour A, Das S, Sehrawat T, Gupta Y. Depression among patients with diabetes mellitus in North India evaluated using patient health questionnaire-9. Indian journal of endocrinology and metabolism. 2015 Mar;19(2):252.
- Sweileh WM, Abu-Hadeed HM, Al-Jabi SW, Sa’ed HZ. Prevalence of depression among people with type 2 diabetes mellitus: a cross sectional study in Palestine. BMC public health. 2014 Dec;14(1):163.
- World Health Organization. Depression Fact sheet N8 369. 2012. Available at: http://www.who.int/mediacentre/factsheets/fs369/en/. Accessed May 12, 2016.
- Al-Khathami AD, Ogbeide DO. Prevalence of mental illness among Saudi adult primary-care patients in Central Saudi Arabia. Saudi Med J 2002; 23(6): 721e724.
- Anderson RJ, Freedland KE, Clous RE, Lustman PJ. The prevalence of comorbid depression in adults with diabetes: a meta-analysis. Diabetes Care 2001; 24: 1069–1078.
- Ali S, Stone MA, Peters JL, et al. The prevalence of co-morbid depression in adults with type 2 diabetes: a systematic review and meta-analysis. Diabet Med 2006; 23: 1165–1173.
- Dunbar JA, Reddy P, Davies-Lameloise N, et al. Depression: an important comorbidity with metabolic syndrome in a general population. Diabetes Care 2008; 31: 2368–2373.
- Egede LE, Zheng D, Simpson K. Comorbid depression is associated with increased health care use and expenditures in individuals with diabetes. Diabetes Care 2002; 25: 464–470.
- Medved V. The comorbidity of diabetes mellitus. Psychiatria Danubina 2009; 21(4): 585e588.
- Koenig HG, Al Zaben F, Sehlo MG, Khalifa DA, Al Ahwal MS, Qureshi NA, et al. Mental health care in Saudi Arabia: past, present and future. Open J Psychiatry [Internet] 2014; 4(2): 113e130.
- Rotella F, Mannucci E. Depression as a risk factor for diabetes: a meta-analysis of longitudinal studies. J Clin Psychiatry. 2013;74: 31–37.
- Campayo A1, de Jonge P, Roy JF. Depressive disorder and incident diabetes mellitus: the effect of characteristics of depression. Am J Psychiatry. 2010 May; 167(5):580-8.
- Williams MM, Clouse RE, Lustman PJ. Treating depression to prevent diabetes and its complications: Understanding depression as a medical risk factor. Clin Diabetes 2006;24:79‑
- Chen PC, Chan YT, Chen HF, et al. Population-based cohort analyses of the bidirectional relationship between type 2 diabetes and depression. Diabetes Care. 2013;36:376–382.
- Golden SH, Lazo M, Carnethon M, et al. Examining a bidirectional association between depressive symptoms and diabetes. JAMA. 2008;299:2751–2759.
- Pan A, Lucas M, Sun Q, et al. Bidirectional association between depression and type 2 diabetes mellitus in women. Arch Intern Med. 2010;170:1884–1891.
- AlHadi AN, AlAteeq DA, Al-Sharif E, Bawazeer HM, Alanazi H, AlShomrani AT, Shuqdar RM, AlOwaybil R. An arabic translation, reliability, and validation of Patient Health Questionnaire in a Saudi sample. Annals of general psychiatry. 2017 Dec;16(1):32.
- Ali N, Jyotsna VP, Kumar N, Mani K. Prevalence of depression among type 2 diabetes compared to healthy non diabetic controls. J Assoc Physicians India. 2013 Sep;60:31-3.
- Lunghi C, Moisan J, Grégoire JP, Guénette L. Incidence of depression and associated factors in patients with type 2 diabetes in Quebec, Canada: a population based cohort study. Medicine. 2016 May;95(21).
- Lustman PJ, Griffith LS, Clouse RE. Depression in adults with diabetes: Results of 5-yr follow-up study. Diabetes Care 1988;11:605-612.
- Egede LE, Zheng D. Independent factors associated with major depressive disorder in a national sample of individuals with diabetes. Diabetes Care 2003;26:104–111.
- Bensbaa S, Agerd L, Boujraf S, Araab C, Aalouane R, Rammouz I, et al. Clinical assessment of depression and type 2 diabetes in Morocco: Economical and social components. J Neurosci Rural Pract. 2014; 5(3):250-3.
- El Mahalli AA. Prevalence and predictors of depression among type 2 diabetes mellitus outpatients in Eastern Province, Saudi Arabia. International journal of health sciences. 2015 Apr;9(2):119.
- Al-Mohaimeed AA. Prevalence and factors associated with anxiety and depression among type 2 diabetes in Qassim: A descriptive cross-sectional study. Journal of Taibah University Medical Sciences. 2017 Oct 1;12(5):430-6.
- De Groot M, Anderson R, Freedland KE, et al. Association of depression and diabetes complications: a meta-analysis. Psychosom Med. 2001;63:619–630.
- Lin EH, Rutter CM, Katon W, et al. Depression and advanced complications of diabetes: a prospective cohort study. Diabetes Care. 2010;33:264–269.
- Lustman PJ, Anderson RJ, Freedland KE, et al. Depression and poor glycemic control: a meta-analytic review of the literature. Diabetes Care. 2000;23:934–942.
- Mishra AK, Kumar S, Ahmad A, Kumar G, Singh KK, Saha KK, Kumar A, Kumar R. Prevalence of Depression in Diabetes Mellitus and Its Determinants. International Journal of Scientific Study. 2017 Jul 1;5(4):151-4.
- DejenieHabtewold T, Radie YT, Sharew NT. Prevalence of depression among type 2 diabetic outpatients in black lion general specialized hospital, Addis Ababa, Ethiopia. Depression research and treatment. 2015;2015.
- Raval, E. Dhanaraj, A. Bhansali, S. Grover, and P. Tiwari, “Prevalence & determinants of depression in type 2 diabetes patients in a tertiary care centre,” Indian Journal of MedicalResearch;2010: 132( 8): 195–200.
- Ahmad A, Abujbara M, Jaddou H, Younes NA, Ajlouni K. Anxiety and Depression Among Adult Patients With Diabetic Foot: Prevalence and Associated Factors. Journal of clinical medicine research. 2018 May;10(5):411.
- Paulraj S, Rajasekaran S & Mathew AC. PREVALENCE OF DEPRESSION AND ITS ASSOCIATED FACTORS IN ADULTS WITH DIABETES MELLITUS: A CROSS-SECTIONAL STUDY IN A TERTIARY CARE CENTRE. Advanced Medical Sciences: An International Journal (AMS); 2017:4(1/2/3).
- Dahal P,Balamurugan G &Basavaraja AU. Prevalence and Predictors of Depression among Diabetes Mellitus in Adult Population. J Psychiatry 2017, 20:6.
- Nawaz AS, Mane AB, Ramakrishna MR. Diabetes and depression: Impact of depression on self-care among patients with type 2 diabetes. International Journal of Medical Science and Public Health. 2015 Jul 1;4(7):901-5.
- Roy T, Lloyd CE, Parvin M, Mohiuddin KG, Rahman M. Prevalence of co-morbid depression in out-patients with type 2 diabetes mellitus in Bangladesh. BMC psychiatry. 2012 Dec;12(1):123.
Corresponding Author
Layla Mansour Alotaibi
Family Medicine Resident
DOI: https://dx.doi.org/10.18535/jmscr/v6i10.107
