Title: A Cross sectional Study on role of MRI and its Clinico-Radiological correlation of Patients with White Matter Disease
Authors: Dr Saif Rahman, Dr Ahmad Rizwan Karim, Dr Annugya Mimansa
DOI: https://dx.doi.org/10.18535/jmscr/v6i10.82
Abstract
Objectives: our study was to evaluate the clinico and radiological correlation and to find the role of MRI as an investigative modality for diagnosis of patients with white matter diseases.
Methodology: A total of 30 cases of white matter lesions were selected for this study. A detail history, clinical examination and relevant investigations were performed to all cases. All the patients were examined with 1.5 Tesla systems (Toshiba Medical System). Head coil was used in all the patients. A combination of T1 and T2 weighted and FLAIR sequences and post gadolinium T1 weighted was obtained in each patient.
Results: Data was analyzed by using simple statistical methods with the help of MS-Office software.
Conclusions: Multiple Sclerosis was the most common white matter disease. Female was more preponderance than male. Patients with second or third decade of life were commonly suffered with MS. Acute Disseminated Encephalomyelitis and Progressive Multifocal Leukoencephalopathy were the second most common disorders of white matter. Cerebral white matters with asymmetric and patchy involvement were seen in all cases of ADEM. Hence, MRI is one of the best invaluable choices for the detection of white matter diseases.
Keywords: White matter disease, Multiple sclerosis, ADEM, MRI.
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