Title: Comparison of Mortality Predictive Scoring Systems in PICU Patients

Authors: Dr S.K Valinjkar, Dr Sukena Susnerwala, Dr Bushra Ansari, Dr Tejasi Sawant

 DOI:  https://dx.doi.org/10.18535/jmscr/v6i10.51

Abstract

Rapidly developing the intensive care units [ICUs] created the need for quantitative and clinically relevant surrogates to evaluate the effectiveness of the management protocols. Predictive scoring systems have been developed to measure the severity of disease and prognosis of patients in the intensive care unit [ICU]. Such scoring systems are useful in clinical decision making, standardizing research and comparing the quality of patient care across ICUs. The outcome of the ICU patients in both adults and children depends on many factors present within the first 24 hours of admission. Many scoring systems have been developed for the ICU populations but very few are actually used in practice. In this study, 4 such scoring systems – namely APACHE II, SOFA, MODS and PRISM shall be studied and compared.

References

  1. Vincent JL, de Mendonça A, Cantraine F, et al. Use of the SOFA score to assess the incidence of organ dysfunction/failure in intensive care units: results of a multicenter, prospective study. Working group on "sepsis-related problems" of the European Society of Intensive Care Medicine. Crit Care Med. 1998;26 (11):1793-800. PMID 9824069.
  2. Ferreira FL, Bota DP, Bross A, et al. Serial evaluation of the SOFA score to predict outcome in critically ill patients. JAMA. 2001;286(14):1754-8. PMID 11594901.
  3. Marshall JC, Cook DJ, Christou NV, et. al. Multiple organ dysfunction score: a reliable descriptor of a complex clinical outcome. Crit Care Med. 1995 Oct;23(10):1638-52. Review.
  4. Moreno R, Vincent JL, Matos R, Mendonça A, Cantraine F, Thijs L, Takala J, Sprung C, Antonelli M, Bruining H, Willatts S. The use of maximum SOFA score to quantify organ dysfunction/failure in intensive care. Results of a prospective, multicentre study. Working Group on Sepsis related Problems of the ESICM. Intensive Care Med 1999 Jul;25(7):686-96PMID 10470572.
  5. de Mendonça A, Vincent JL, Suter PM, Moreno R, Dearden NM, Antonelli M, Takala J, Sprung C, Cantraine F. Acute renal failure in the ICU: risk factors and outcome evaluated by the SOFA score. Intensive Care Med 2000 Jul;26(7):915-21. PMID 1099010
  6. Janssens U, et al. Value of SOFA (Sequential Organ Failure Assessment) score and total maximum SOFA score in 812 patients with acute cardiovascular disorders [abstract]. Crit Care 2001;5 (Suppl 1):P225.
  7. Knaus WA, Draper EA, Wagner DP. APACHE II: a severity of disease classification system. Crit Care Med. 1985;13(10):818-29. PMID 3928249.
  8. Kane SP. Acute Physiology and Chronic Health Evaluation (APACHE II) Calculator. ClinCalc: http://clincalc.com/IcuMortality/APACHEII.aspx. Updated October 24, 2015. Accessed December 21, 2015.
  9. Batista CC, Gattass CA, Calheiros TP, Moura RB. Avaliaçãoprognóstica individual na UTI: é possível diferenciar insistência terapêutica de obstinação terapêutica? Rev Bras TerIntensiva. 2009;21:247–54. 10.1590/S0103‐507X2009000300003 [PubMed]
  10. Gunning K, Rowan K. ABC of intensive care: outcome data and scoring systems. BMJ. 1999;319:241–4. [PMC free article] [PubMed]
  11. Kalil Filho WJ, Delgado AF, Schvartsman B, Kimura HM. Análise Clínica e Prognóstica da Síndrome de Disfunção Orgânica Múltipla. Pediatria (São Paulo) 1995;17:143–7.
  12. Seneff M, Knaus WA. Predicting patient outcome from intensive care: a guide to APACHE, MPM, SAPS, PRISM, and other prognostic scoring systems. J Intensive Care Med. 1990;5:33–52.
  13. Shann F. Are we doing a good job: PRISM, PIM and all that. Intensive Care Med. 2002;28:105–7. [PubMed].

Corresponding Author

Dr Bushra Ansari