Abstract
Leiomyoma is the most common type of benign tumor of uterus and carry 70-80% of cumulative incidence in reproductive age group. Our study was conducted to analyse the clinicopathological correlation, spectrum of variants and secondary changes of leiomyoma of uterus. The clinical presentation, histological pattern and combination with other reproductive tract lesions were also studied. The time period was two years from September 2016 to August 2018. A total of 100 hysterectomy and myomectomy specimens received in pathology department of T.S. Misra Medical College, were included in the study. Most of the patients of leiomyoma were present in their reproductive age. Hyaline change and calcification are commonly seen in longstanding leiomyomas and are clinically asymptomatic. In our study the incidence remains highest in the child bearing age group. Intramural leiomyoma was present in highest number. The presence of proliferative phase of endomentrium, endometrial hyperplasia, adenomyosis and cystic ovaries indicated association of leiomyoma with high estrogen levels in the blood.
References
- KIstner RW. Gynecology Principles and practices, Chicago yearbook medical publishers Inc. 1964:261.
- Baird DD, Dunson DB, Hill MC, Cousins D, Schedman JM. High cumulative incidence of uterine leiomyomas in black and white women. Ultrasound incidence of uterine leiomyomas in black and white women. Ultrasound evidence. Am J Obstet Gynecol.2003.188(1):100-107.
- Ibrar F, Raiza S, Dawood NS, Jabeen A. Frequency of fibroid uterus in multipara women in a tertiary care centre in Rawalpindi. J Ayub Med Coll Abbottabad. 2010; 22(3):155-7.
- Akinyemi BO, Adewoye BR, Fakoyata. Uterinefibroid: Areview. Niger J med. 2004;13:318-329.
- Lefebure G, Viols G A llaire C et al.The management of uterine leiomyoma: Clinical Practice Gynecological Committee. Obstet Gynecol Can. 2003: 25:396-418.
- Bhasker Reddy D.Study of 325 cases of fibromyoma of uterus. J Obstet Gynecol India.1963;13:340.
- Usha, Narang BR, Tiwari PV et al. Clinicopathological study of benign tumors od=f the uterus.Indian Med Gazette.1992;12:68-71.
- Ashrof T.Management of uterine leiomyoma. J Coll physicians Surg Pak.1997;7:160-162.
- Zimmermann A Bernuit D Gerlinger C et al. Prevalace, symptoms and management of uterine fibroid. An international internet based survey of 21,746 women.BMC women’s health.2012,12:6.
- Khyade RL.A study of menstrual disturbances in cases of fibroid uterus.Int J Reprod Contracept, Obstet Gynecol. 2017;6(6):2494-7.
- Shaheen S, Naheed T, Sadaf F, Rahim R. Menorrhagia due to fibroids and its management. JSOGP.2013;3(4):231-5.
- Chhabra S, Ohri N. Leiomyoma of uterus-A clinical study. J Obstet Gynacol India.
- Bhat RA, Kumar NP. Experience with uterine leiomyomas at a teaching referral hospital in India. J Gyneacol Surg. 2006;22 (4):143-50.
- Padubidri VG, Daftary SN. Fibromyomas of the uterus. In: Howkins and Bourne Shaw’s Textbook of Gynaecology. 12thNew Delhi, India: Churchill Livingstone;1999:275-285.
- Sangle NA, Lele SM. Uterine mesenchymal tumors. Indian J Pathol Micribiol. 2011;54:243-53.
- Rosai J. Leiomyoma.In: Textbook Surgical Pathology. 9th New Delhi, India: Elsevier;2004;2:1603-1608.
- Zaloudek C Hendrikson MR. Mesenchymal tumors of the uterus.In: Blaustein’s Pathology of the Female Genital Tract.5th New Delhi, India: Springer;2004.
- Munuswamy MM, Sheelaa WG, Vijaya P L.Clinical presentation and prevalence of uterine fibroids: A 3-years study in 3-decade rural South Indian women.Int J Reprod Contracep tObstet Gynecol.2017 Dec;6(12):5596-5601.
Corresponding Author
Dr Poornima Mishra
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
DOI: https://dx.doi.org/10.18535/jmscr/v6i10.34
