Title: Seroprevalence of Hepatitis B in replacement and voluntary blood donors at Tertiary care center, M.Y.H. Indore
Authors: Dr Priyanka Solanki, Prof. Dr Ashok Yadav, Dr Khushboo Likhar
DOI: https://dx.doi.org/10.18535/jmscr/v6i9.194
Abstract
Background: Blood transfusion is a potentially significant route of transmission of infections to the recipient.
Objective: The aim of study is to determine the seroprevalence of Hepatitis B among replacement and voluntary donors in blood bank at tertiaty care center, Indore.
Material and Method: The present study included 75090 blood donors attending blood bank at tertiary care center, Indore. All the donor samples were screened for detection of surface Ag of hepatitis B. The seroprevalence of hepatitis B positive donors was calculated over a period of three years since January 2015 to December 2017.
Result: In this study, out of total 75090 blood donors, replacement donors were 6710 (8.93%) while voluntary donor were 68380 (91.06%). Total 854 cases (1.13%) were HbsAg positive in the duration of three year study period. Here out of 6710 replacement donors, 246 cases (3.66%) were HbsAg positive while out of 68380 voluntary donors, 608 cases (0.88%) were HbsAg positive. Voluntary donors are more as compared to the replacement donors. Number of HbsAg positive patients were found to more in replacement donor as compared to the voluntary donors.
Conclusion: The seroprevalence of Hepatitis B in present study is high among replacement donors. Strict quality control, proper counselling of donors and training of blood transfusion personnel including deferring of suspected donors may reduce transmission of HbsAg.
Keywords: Blood donor, Hepatitis B.
References
- Islam MB. Blood transfusion services in Bangladesh. Asian Journal of Transfusion Science 2009 ; 3:108-110.
- Shepard CW, Simard EP, Finelli L, Fiore AE, Bell BP. Hepatitis B virus infection: Epidemiology and vaccination. Epidemiol Rev 2006;28:112-25.
- Lavanchy D. Hepatitis B virus epidemiology, disease burden, treatment, and current and emerging prevention and control measures: A review. J Viral Hepat 2004,11:97-107.
- Prevention of Hepatitis B in India; An Overview, World Health Organization, Regional Office for South-East Asia, New Delhi, August 2002. (http://whqlibdoc.who.int/searo/2002/SEA_Hepat.-5.pdf)
- Government of India. Drugs and Cosmetics Rules, 1945 (amended till 30th June 2005). Accessed on 25-02-2015 from http://www.cdsco.nic.in/html/Drugs&CosmeticAct.pdf
- National Blood policy by National AIDS Control organization, ministry of health and family welfare Government of India, New Delhi. June 2003 (reprint 2007). Accessed on 25-02-2015 from http://www.naco.gov.in/upload/2014%20mslns/BTS/National%20Blood%20Policy.pdf
- Sheetal arora et.al. Study of Transmission Transmitted Infections (TTI) Prevalence in a Large Sample of 25,000 Blood Donors at a Tertiary Care Center,Annals of Applied Bio-Sciences, Vol. 4; Issue 3: 2017 e-ISSN: 2349-6991; p-ISSN: 2455-0396
- Nagarekha Kulkarni Analysis of the seroprevalence of HIV, HBsAg, HCV and syphilitic infections detected in the pretranfusion blood: A short report IJBTI – International Journal of Blood Transfusion and Immunohematology, Vol. 2, 201 2. ISSN – [2230-9020].
- Arora D, Arora B, Khetarpal A. Seroprevalence of HIV, HBV, HCV and syphilis in blood donors in Southern Haryana. Indian J Pathol Microbial 2010;53(2):308–9.
- Tulika Chandra, Ashutosh Kumar, Ashish Gupta. Prevalence of transfusion transmitted infections in blood donors: an Indian experience. Tropical Doctor 2009;39(3):152–4.
- Nilima Sawke, Sawke GK, Chawla. Seroprevalence of common transfusion – Transmitted infections among blood donors. People’s journal of scientific research 2010;3(1):5–7.