Title: Carbetocin versus oxytocin for the prevention of postpartum haemorrhage during caesarean section-A study of 100 cases in Combined Military Hospital, Momenshahi

Authors: Maj Nasrin Hasan, Lt Col Apple Mahmud Anwar, Lt Col Md. Golam Mostofa Sarwar, Maj Rezwana Sharmin Snigdha

 DOI:  https://dx.doi.org/10.18535/jmscr/v6i9.176

Abstract

Postpartum bleeding or postpartum hemorrhage (PPH) is often defined as the loss of more than 500 ml in vaginal delivery or 1,000 ml of blood in caesarean section within the first 24 hours following childbirth. It occurs more commonly in those who: already have anemia, obesity, multiple pregnancy, older than 40 years of age. It also occurs more commonly following caesarean sections, during medications are used to start labor, during the use of a vacuum or forceps. In the developing world about 1.2% of deliveries are associated with PPH and when PPH occurred about 3% of women died. Globally it occurs about 8.7 million times and results in 44,000 to 86,000 deaths per year making it the leading cause of death during pregnancy. In UK, during2000–2002, PPH was the second most frequent cause of maternal death. Caesarean section is an agonized risk factor for PPH and the worldwide caesarean delivery rate is increasing It has been found that a hormone named oxytocin, plays an important role to stimulate the uterus to contract shortly after the baby is born. Another drug named carbetocin is also used to control postpartum hemorrhage. So, in this study our main objective to find most crucial and effective drug of PPH prevention by comparing effectiveness of carbetocin vs. oxytocin.

Keywords: Postpartum hemorrhage, caesarean sections, carbetocin, oxytocin.

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Corresponding Author

Maj Nasrin Hasan

(MCPS, FCPS), Classified Specialist, Obstetrics and Gynaecology, CMH-Momenshahi