Title: Clinical and Histopathological Studies of Oral Mucosal Lesions (Non- Neoplastic) in Patients of Lucknow Region

Authors: Dr Abha Mishra, Dr Neetu Shukla, Dr Manaswi Chaubey, Dr Mamta Dwivedi, Dr P.K. Chaturvedi

 DOI:  https://dx.doi.org/10.18535/jmscr/v6i8.19

Abstract

Oral cavity is more prone for changes with advancing age as well as a result of the environmental and life style related factors. Oral mucosal lesions may be due to infection (bacterial, viral, fungal), local trauma and or irritation (traumatic keratosis, irritational fibroma, burns), systemic disease (metabolic or immunological), or related to lifestyle habits such as the usage of tobacco, areca nut, betel quid, or alcohol.

Smoking, drinking and tobacco chewing have been positively associated with oral lesions such as Leukoplakia, oral sub mucosal fibrosis and oral lichen planus which have the potential risk for malignant transformation. Out of 239 patients, 123 (51.5%) were male and 116 (48.5%) patients were female, and M: F ratio is 1.09:1. The distribution of lesion varied with age and maximum cases  (25.9%)) were reported in age group of 21 -30 followed by (21.8%) cases in 31 -40, (17.6%) in age group of 41-50.Least cases (2.1%) were reported in age group of 70-80 years. In concern with clinical features 137 patients could not open their mouth completely, 99 made complain of burning sensation and 95 patients had complained of pain. Other complains were   altered taste.

Aphthous ulcers were the most common diagnosis (48.9%) followed by Leukoplakia (22.2%) and Oral lichen planus (8.8%). Oral sub mucosal fibrosis were reported in 3.8% .In 0.8% cases Pemphigus vulgaris were diagnosed. Lesion distribution by location was known for 230 cases .The most common site was the buccal mucosa (25.7%)) followed by gingiva (16.5%).An Aphthous ulcer is more common in our study. The present study was therefore designed to evaluate relative prevalence of biopsied Non-Neoplastic oral mucosal lesion in relation to demographic and localisation of lesion based on a retrospective review of 239 patients of Lucknow region visited in OPD of ENT department of TSM hospital.

Keyword: OML: Oral Mucosal Lesion, OSFL: - Oral Sub Mucosal fibrosis Lesion, Aphthous ulcer, Leukoplakia.

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Corresponding Author

Dr Neetu Shukla

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