Details
Category: Volume 06 Issue 07 July 2018
Hits: 1476

Title: Fine Needle Aspiration Cytology (FNAC) of Thyroid Lump of Patients, Attending in Tertiary Care Hospital, at P.M.C.H., Patna

Authors: Dr Uday Shanker Pandey, Dr Nawanita Kumari

 DOI:  https://dx.doi.org/10.18535/jmscr/v6i7.158

Abstract

Objective: Fine Needle Aspiration Cytology (FNAC) is the most common modality for the diagnosis of thyroid lump or nodule. Present study was undertaken to evaluate the benign or malignant Pathology of thyroid swelling by the help of FNAC, of Patient attending in our hospital.

Material and Method: A total of 124 patients with midline neck swelling were send to our Department for Fine Needle Aspiration Cytology, from ENT OPD or IPD. After detailed history and clinical examination, FNAC was done under full aseptic precaution and 4-5 slides were prepared. After fixation, slides were stained with Giemsa and papanicolau stain and seen under low to high power magnification.

Result: Out of 124 patients, 110 (88.7%) were female and 14 (11.3%) patient were male. Female to male ratio was 7.85:1. 91 (82.72%) female were belongs to 31-50 year of age. Out of 124 cytological smear findings, 102 (82.25%) were benign in nature. Out of 102 smear which was benign or normal cellular morphology, 58 (56.86%) cases were diagnosed as nodular colloid goiter, 11 (10.78%) patients smear shows features of benign cystic lesion, 32 (31.37) patient were having simple colloid goiter and 1 (0.98%) patient showing hyper plastic thyroid nodular features. 20(16.12%) patients were suspicious because of presence of cellular atypia, while 2(1.61%) patients were malignant in nature.

Conclusion: Fine needle aspiration is on inexpensive and outdoor procedure. It can be performed under clinical setting and economy of the patients in our country. Moreover, there always a need to simplify the surgical procedure and to ensure that it should be done in the most effective manner, Particularly in India. 

Keywords: FNAC, Thyroid, Malignant, Pap Smear, Stain.

References

  1. Werner Sc. Historical resume in Braveman (E, utiger RD(eds); The thyroid : A fundamental and clinical text, 6th edition. Philadelphia, TB Lippincott; 1991: chapter 1:3-6
  2. Suresh kumar, Shakil Aquil, Abdullah pahar, Role of Fine needle aspiration cytology in thyroid disease, Journal of Surgery Pakistan (International) 13(1) January — March 2008
  3. Muhammad Tariq, FNAC of thyroid nodule; Diagnostic Accuracy of Fine Needle Aspiration Cytology, professional Med, Dec 2010; 17(4):589-597
  4. Larry Jameson.J, Anthony P.Weetman. Disease of the thyroid gland, Harrison's Principle of Internal Medicine, vol.2, 18th edition, 2012; 2104 — 2125
  5. Ashcraft MW, Van Herle AJ, 1981 Management of thyroid nodules, 1; Physical examination, blood tests, X-ray tests 8‘. ultrasonography, Head Neck Surgery 3; 216- 230
  6. Castro MR, Gharib H, 2003, Thyroid Fine Needle Aspiration biopsy: Progress, Practice and Pitfalls Endocr. Pract 9: 128 — 136
  7. Carpi A, Sagri penti A, Nicotine et al 1998. Large needle aspiration biopsy for reducing the rate of inadequate cytology on fine needle aspiration specimen from palpable thyroid nodule. Biomed Pharmacother 52 : 303 — 307.
  8. A Diamahtis et al. Fine needle aspiration( FNA) biopsy: historical aspects folic histochemica Et Cytobiologica vol. 47, no. 2, 2009 : 191 — 197
  9. Kaplan MM. Evaluation of Thyroid Nodule by needle aspiration. In Braverman LE, utiger RD editors, The Thyroid, 8th edition, Philadelphia: Lippincott Williams and Wilkins 2000 : 441 — 451
  10. Namou Kim, Pierre Lavertu. Evaluation of a Thyroid nodule. Disorders of the Thyroid. otolaryngol Clin N Am 2003; 36: 17 — 33.
  11. Pepper GM, Zwickler D, Rosen Y. Fine needle aspiration biopsy of the thyroid nodule. Arch Intern Med 1989;149:594-6
  12. Cramer H. Fine needle aspiration cytology of the Thyroid. An appraisal. Cancer Cytopath 2000;90:325-9
  13. Kini SR. Techniques of Fine needle aspiration biopsy. In: Guide to clinical aspiration cytology: thyroid. Newyork: Igaku-Shoin:1987.p.5 — 12.
  14. Surgical pathology by Rosai and Ackerman's -9th edition
  15. Pathological basis of disease — Robins and Cotran(8th edition)
  16. Text book of Pathology — By Harsh Mohan (6th edition)

Corresponding Author

Dr Uday Shanker Pandey

Associate Professor, Department of Pathology, Patna Medical College, Patna