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Category: Volume 06 Issue 07 July 2018
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Title: Correlation of fine needle aspiration cytology (FNAC) with histopathology in palpable breast lesions: A study of 200 cases from a tertiary care center in South India

Authors: Bhavya P Mohan, Sharath K Krishnan, Prasad PH, Lovely Jose, Nisha M Das, Feroze M

 DOI:  https://dx.doi.org/10.18535/jmscr/v6i7.156

Abstract

Background: Palpable breast lesions are one of the commonest presentations in general and oncological surgical practice. Breast cancer is the commonest cancer affecting women worldwide. Fine needle aspiration cytology (FNAC) is an ideal initial diagnostic modality in the management of palpable breast lesions which helps to avoid unnecessary surgical intervention in benign breast lesions and to confirm preoperative diagnosis in malignant breast lesions.

Materials and Methods: Cytohistopathological correlation was done in 200 cases who presented with a palpable breast mass in FNA clinic of Dept. of Pathology, Government Medical College, Thrissur, Kerala.

Results: A total of 200 cases was studied which included 87 benign cases (43.5%), 105 malignant cases (99 cases diagnosed as carcinoma and 6 cases as suspicious of malignancy) (Total 52.5%), 5 proliferative lesions with atypia (2.5%) and 3 inadequate cases (1.5%). Histopathological diagnosis of all 200 cases was collected and analyzed. There was a discrepancy in 5 cases (2.5%). Sensitivity, specificity, positive predictive value and negative predictive value of FNA for diagnosing benign lesions were found to be 98.8%, 96.3%, 95.6% and 99% and for malignant lesions the values were 96.3%, 98.8%, 99% and 95.6%  respectively. The diagnostic accuracy of FNAC in this study was 97.45%.

Conclusion: FNAC is a reliable primary screening technique for palpable breast lumps with high diagnostic accuracy and good specificity and positive predictive value, especially for malignant lesions.

Keywords: Breast, Palpable, Correlation, Fine Needle Aspiration, Histopathology.

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Corresponding Author

Dr Sharath K Krishnan

Assistant Professor, General Surgery, Govt.Medical College, Thrissur, Kerala, India

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