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Category: Volume 06 Issue 07 July 2018
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Title: Clinical and Cytogenetic Analysis of a Baby with Vestigial Tail and Limb Defects

Authors: Deepthy Vijayaraghavan, Cyril Joseph, Alex George

 DOI:  https://dx.doi.org/10.18535/jmscr/v6i7.94

Abstract

Vestigial tail otherwise called the neuroectodermal appendage is a rare occurrence. Very few cases have been reported in literature. Several congenital anomalies may coexist with vestigial tails. Associated cutaneous stigmata like dermal sinus, lipoma, hyperpigmented skin, hair patch have also been documented. In this study an attempt has been made to investigate the clinical and cytogenetic profile of a female infant with a tail like structure in the lumbosacral region associated with multiple limb defects. Cytogenetic profiles of family members were studied by performing karyotype analysis to look for chromosome level involvement in the development of this condition. The cytogenetic profiles were found to be normal. The tail was excised successfully without neurological deficits and limb defects were surgically corrected.

Keywords- Vestigial tail, Limb defects, Symbrachydactyly, Club foot, Karyotyping

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Corresponding Author

Alex George

Jubilee Centre for Medical Research, Jubilee Mission Medical College & Research Institute, Thrissur, Kerala – 68000