Title: Antral Follicle Count and AMH Level for Ovarian Reserve Comparison

Authors: Dr Shrikant Adsul, Dr Rajendra Rajguru, Dr Neeta Adsul, Dr Asmita Patil

 DOI:  https://dx.doi.org/10.18535/jmscr/v6i7.78

Abstract

Background: The chronological age at which menopause happens is evocative that reproductive aging is flexible amongst females, and shows that age is not a lone factor indicating the females’ reproductive potential. Various tests have been used to determine ovarian reserve, they are primarily used in Infertility clinics. Endocrine markers like anti-Mullerian hormone, estrogen and follicle stimulating hormone and  inhibin B indirectly specify the increasing follicle count. The aim of the present study was to compare the antral follicle count and AMH level for ovarian reserve.

Materials and Methods: The present study was conducted in the department of gynecology for a period of 1 year. Plasma was separated and frozen at -70 degree Celsius. The demographic details of all the subjects was recorded in the forms. All the subjects were asked about age at menarche. The level of AMH was estimated in ng/ml. Student t test was used as a test of significance and probability value of less than 0.05 was considered as significant.

Results: The study involved 57 females with the mean age between 35.78 +/- 5.32 years. The median age of the subjects was 34 years with the range between 28-39 years. Between 20-25 years of age, the mean antral follicle count was 15.6+/-4.1. Between 26-30 years of age, the mean antral follicle count was 14.5+/- 4.9. The level of AMH amongst subjects who smoked was 1.8 (0.8–3.5) and those who didn’t smoke was 2.2 (1.2–3.2). The level of AMH amongst subjects who consumed alcohol was 2.2 (1.0–3.3) and those who didn’t was 1.7 (1.2–3.2).

Conclusion: From the above study, we can conclude that levels of AMH and AFC significantly correlate with reproductive age.

Keywords: Antral follicle, Infertility, Mullerian.

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Corresponding Author

Dr Shrikant Adsul

DNB FCPS DGO MBBS Gyneacology

Assistant Professor At Rajiv Gandhi Medical College Kalwa