Title: The Diagnosis of Serous Forms of Extra pulmonary Tuberculosis: Is PCR Definite Answer?
Authors: Dr Rameshwar Dayal, Dr S.S. Gupta, Dr Manish Bansal, Dr Varun Gupta
DOI: https://dx.doi.org/10.18535/jmscr/v6i7.73
Abstract
Objectives: To study the evaluation the use of polymerase chain reaction (PCR) in patients of serous form of extra pulmonary tuberculosis.
Methods: We studied all patients of serous form of extra pulmonary tuberculosis with high suspicion of index in our hospital from July 2014 to June 2017 in department of medicine, FHMC and Hospital, Etmadpur, Agra. All patients were subjected for detailed clinical examinations, investigations and PCR study and statistically analysed.
Results: A total of 320 patients were included in study. 230 patients were suspected as tubercular and 90 patients were non tubercular on the ground of clinical and cytobiochemical analysis. Among 230 patients, only 85 patients were PCR positive (41.38%) for tuberculosis while out of 90 non tubercular patients, none was PCR positive (100%). Thus PCR study showed that sensitivity was 41.38% and specificity was 100%.
Conclusion: PCR is a rapid diagnostic technique having high degree of specificity for the detection mycobacterium tuberculosis in the serous forms of extra pulmonary tuberculosis.
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