Title: Management of Various Bleeding Problems in Dental Patients: An Approach to Normal Hemostatic System and the Patient's Specific Coagulation Defect

Author: Bhanupriya Mahant

 DOI:  https://dx.doi.org/10.18535/jmscr/v6i7.61

Abstract

Management of various bleeding problems in Dental patients is very critical issue in today clinical practice. Dentists must be conscious of the collision of bleeding disorders on the supervision of their patients. Proper dental and medical evaluation of patients is therefore necessary before handling, especially if an invasive dental method is planned. Patients with gentle bleeding disorders can be treated in a most important care setting after conference with the hematologist, while patients with a reasonable to severe level of bleeding disorder who require all-encompassing dental procedures are best treated in a hospital setting. Dental care providers must straight away report cases of prolonged bleeding, dysphagia, or involvedness speaking and breathing following dental events to the patient’s hematologist.

Keywords: Bleeding Problems, Dental Patients.

References

  1. Lockhart PB, Gibson J, Pond SH, Leitch J. Dental management considerations for the patient with an acquired coagulopathy. Part 1: Coagulopathies from systemic disease. Br Dent J 2003; 195(8):439–45.
  2. Meechan JG, Greenwood M. General medicine and surgery for dental practitioners Part 9: haematology and patients with bleeding problems. Br Dent J 2003; 195(6):305–10.
  3. Patton LL. Bleeding and clotting disorders. In: Burket’s oral medicine: diagnosis and treatment. 10th ed. Hamilton (ON): BC Decker; 2003. p.454–77.
  4. Blinder MA. Bleeding disorders. [Web site of the Washington University School of Medicine]. Available from URL: http://hematology.im.wustl.edu/ conferences/presentations/blinder080604.ppt.
  5. Lusher JM, Roth DA. The safety and efficacy of B-domain deleted recombinant factor VIII concentrates in patients with severe haemophilia A: an update. Haemophilia 2005; 11(3):292–3.
  6. Schlesinger KW, Ragni MV. Safety of the new generation recombinant factor concentrates. Expert Opin Drug Saf 2002; 1(3):213–23.
  7. Manno CS. The promise of third-generation recombinant therapy and gene therapy. Semin Hematol 2003; 40(3 Suppl 3):23–8.
  8. Webster WP, McMillan CW, Lucas ON, and others. Dental management of the bleeder patient. A comparative review of replacement therapy. In: Ala F, Denson LW, editors. Hemophilia. Amsterdam: Excerpta Medica; 1973. p. 33–7.
  9. Walsh PN, Rizza CR, Matthews JM, Eipe J, Kernoff PB, Coles MD, and others. Epsilon aminocaproic acid therapy for dental extractions in haemophilia and Christmas disease: a double blind controlled trial. Br J Haematol 1971; 20(5):463–75.
  10. Walsh PN, Rizza CR, Evans BE, Aledort LM. The therapeutic role of epsilon- Aminocaproic acid (EACA) for dental extractions in hemophiliacs. Ann N Y Acad Sci 1975; 240:267–76.
  11. Golla K, Epstein JB, Cabay RJ. Liver disease: current perspectives on medical and dental management. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2004; 98(5):516–21.
  12. Lockhart PB, Gibson J, Pond SH, Leitch J. Dental management considerations for the patient with an acquired coagulopathy. Part 2: Coagulopathies from drugs. Br Dent J 2003; 195(9):495–501.
  13. Flint SR, Keith O, Scully C. Hereditary hemorrhagic telangiectasia: family study and review. Oral Surgery Oral Med Oral Pathol 1988; 66:440–4.
  14. Nazif M. Local anesthesia for patients with hemophilia. ASDC J Dent Child 1970; 37(1):79–84.
  15. Webster WP, Roberts HR, Penick GD. Dental care of patients with hereditary disorders of blood coagulation. In: Rantoff OD, editor. Treatment of hemorrhagic disorders. New York: Harper & Row; 1968. p. 93–110.
  16. Archer WH, Zubrow HJ. Fatal hemorrhage following regional anesthesia for operative dentistry in a hemophiliac. Oral Surg Oral Med Oral Pathol 1954; 7(5):464–70.
  17. Leatherdale RA. Respiratiory obstruction in haemophilic patients. Br Med J 1960; 30(5182): 1316–20.
  18. Rackoz M, Mazar A, Varon D, Spierer S, Blinder D, Martinowitz U. Dental extractions in patients with bleeding disorders. The use of fibrin glue. Oral Surg Oral Med Oral Pathol 1993; 75(3):280–2.
  19. Napeñas JJ, Patton LL. Bleeding and clotting disorders. In: Glick M, ed. Burket’s Oral Medicine.
  20. 12th ed. Shelton, CT: People’s Medical Publishing House—USA; 2015:463-488.
  21. Pototski M, Amenábar JM. Dental management of patients receiving anticoagulation or antiplatelet treatment. J Oral Sci. 2007;49(4):253-258.
  22. Lockhart PB, Gibson J, Pond SH, Leitch J. Dental management considerations for the patient with an acquired coagulopathy, 1: coagulopathies from systemic disease. Br Dent J. 2003; 195(8):439-445.
  23. De Caterina R, Husted S, Wallentin L, et al. General mechanisms of coagulation and targets of anticoagulants (Section I). Position paper of the ESC Working Group on Thrombosis—Task Force on Anticoagulants in Heart Disease. Thromb Haemost. 2013;109(2013):569-579.
  24. Nizarali N, Rafique S. Special care dentistry, 2: dental management of patients with drug-related acquired bleeding disorders. Dent Update. 2013;40:711-712, 714-716, 718.
  25. Rafique S, Fiske J, Palmer G, Daly B. Special care dentistry, 1: dental management of patients with inherited bleeding disorders. Dent Update. 2013;40(8):613-616, 619-622, 625-626.
  26. Scully C, Diz Dios P, Kumar N. Special Care in Dentistry: Handbook of Oral Healthcare. Philadelphia: Churchill Livingstone Elsevier; 2007.
  27. Valera MC, Kemoun P, Cousty S, Sie P, Payrastre B. Inherited platelet disorders and oral health. J Oral Pathol Med. 2013;42(2):115-124.
  28. Seligsohn U. Treatment of inherited platelet disorders. 2012;18(Suppl 4):161-165.
  29. Aoun N, Noujeim Z, El Toum S. von Willebrand disease revealed after dental post-extractional bleeding: a case report. J Int Oral Health. 2016;8(4):512-517.
  30. Anderson J, Brewer A, Creagh D, et al. Guidance on the dental management of patients with haemophilia and congenital bleeding disorders. Br Dent J. 2013;215(10):497-504.
  31. Franchini M, Mannucci PM. Von Willebrand disease-associated angiodysplasia: a few answers, still many questions. Br J Haematol. 2013;161(2):177-182.
  32. Davie EW, Fujikawa K, Kisiel W. The coagulation cascade: initiation, maintenance, and regulation. Biochemistry 1991;30:10363–70.
  33. Mustard JF, Packman MA. Factors influencing platelet function: adhesion, release, and aggregation. Pharmacol Rev 1970;22:97–187.
  34. Davie EW, Ratnoff OD.Waterfall sequence for intrinsic blood clotting. Science 1964;145:1310–2.
  35. MacFarlane RG. An enzyme cascade in the blood clotting mechanism and its function as a biochemical amplifier.Nature 1964;202:498–9.

Corresponding Author

Bhanupriya Mahant

Peoples College of Dental Sciences and Research Center, Bhopal, MP, India

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