Title: Cytological and Histopathological Correlation of Salivary Gland Lesions

Authors: Neha Sikdar, V. Sriram, Erli Amel Ivan

 DOI:  https://dx.doi.org/10.18535/jmscr/v6i7.21

Abstract

Introduction: Salivary gland lesions are the most commonly involved head and neck swellings ranging from reactive inflammatory to neoplastic, which may be benign or malignant.Though histopathological diagnosis is gold standard for confirmation of fine needle aspiration cytology (FNAC) findings, FNAC is an excellent first-line tool in providing an early diagnosis.

Aims and Objectives: To elucidate the cytomorphological features of various salivary gland lesions on FNAC and explore the diagnostic criteria by correlating with histomorphological findings.

Materials and Methods: The present study was done at the Department of Pathology, Sri Manakula Vinayagar Medical College, Pondicherry. FNAC was done using 24 gauge needle and 5 ml syringe and smears were stained with Haematoxylin & Eosin (H&E) and Giemsa stains. Histopathology was assessed on routine H&E stained paraffin sections. Cyto-histo correlation was done and overall diagnostic accuracy was calculated.

Result: The accuracy of FNAC in diagnosing salivary gland lesions was 72%.Age group between 51-60yrs was found to be the most common for salivary gland lesions and parotid was found to be the most common site for salivary gland lesions.

Conclusion: From this study it was concluded that fine needle aspiration cytology is an excellent first line of investigation for the diagnosis of various salivary gland lesions. However, there still remain few diagnostic dilemmas in which histopathology and immunohistochemistry confirmation is required.

Keywords: Diagnostic accuracy, FNAC, histopathology, salivary gland lesions, sensitivity, specificity.

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Corresponding Author

Dr V. Sriram

Assistant Professor, Department of Pathology, Sri Manakula Vinayagar Medical College and Hospital

Kalitheerthalkuppam, Puducherry, 605107

Email: This email address is being protected from spambots. You need JavaScript enabled to view it., Mob 9500993884