Title: Assessment of Lipid Profile Parameters among Type II Diabetic Patients: An Institutional Based Study

Authors: Dr Mahesh Pal Khatri, Dr Vijayta Modi

 DOI:  https://dx.doi.org/10.18535/jmscr/v6i7.13

Abstract

Background: Diabetic patients have a greater likelihood of having dyslipidemia, hypertension, and obesity. This form of dyslipidemia remains largely undiagnosed or diagnosed late and under treated in high risk populations, such as patient with type- 2 diabetes. The aim of the study is to investigate the relationship between serum lipid profiles in type-2 diabetic patients.

Material & Methods: A cross sectional study done on 200 patients with type 2 diabetes. The participants were already diagnosed as type 2 diabetics and undergoing treatment. According to NCEP-ATPIII guideline, hypercholesterolemia is defined as TC>5.2 mmol/l, high LDL-C when value >2.6 mmol/l, hypertriglyceridemia as TG >3.8 mmol/l and low HDL-C when value <1.0 mmol/l. Dyslipidemia was defined by presence of one or more than one abnormal serum lipid concentration. Diabetes was defined as per American Diabetes Association (ADA) criteria.

Results: The mean age of the males (58.1±2.3) were not statistically different (p=0.6402) from that of the females (57.1±1). The mean waist circumference (WC), hip circumference (HC), Body Adiposity Index (BAI) and Body Mass Index (BMI) of the female subjects were significantly high as compared with the male subjects (p=0.0008, 0.0002, 0.000 and 0.0002 respectively). Among the diabetic individuals, 119(59.5%) individuals had only one abnormal lipid profile parameter, 68(34.0%) had two abnormal lipid parameter and 54(27%) individuals had more than 2 abnormal lipid profile parameter.

Conclusion: We concluded that early diagnosis can be accomplished through relatively inexpensive blood testing and may be utilized for screening high-risk diabetic patients for timely intervention with lipid lowering drugs.

Keywords: Type II Diabetes mellitus, Lipid Profile, Dyslipidemia, BMI.

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Corresponding Author

Dr Vijayta Modi

Assistant Professor, Dept. of Pathology

S.P. Medical College, Bikaner, Rajasthan, India