Title: Fine Needle Aspiration Cytology of Lymph Nodes- An Analysis of 893 Cases

Authors: Dr. Neha Mukesh Goel, Dr N.A. Ramteerthkar, Dr K.R. Sulhyan

 DOI:  https://dx.doi.org/10.18535/jmscr/v6i6.163

Abstract

Objectives: The present study was undertaken to establish the etiologic diagnosis of enlarged lymph nodes and to classify the spectrum of diseases causing lymphadenopathy by Fine needle aspiration cytology.

Methods: The study was carried out over a period of 4 years. Fine needle aspiration cytology was performed in 893 patients presenting with lymphadenopathy. Patients included in the present study were in the age group of 9 months to 80 years.

Results: There were 482 males and 411 females. Maximum number of cases were in the age range of 21-40 years. The most common site of enlarged lymph nodes was cervical group of lymph nodes. Tuberculous lymphadenitis was seen as most common inflammatory disease followed by reactive and acute lymphadenitis. In neoplastic diseases, metastatic tumors in head and neck region were most common followed by lymphomas. 65 patients were HIV positive. In these patients, enlarged lymph nodes were mostly secondary to tuberculosis. Histopathology and cytology correlation was available in only 30 cases. One case of non-specific lymphadenitis was over-diagnosed as non-hodgkin lymphoma on cytology. The accuracy rate was 100% in tuberculous lymphadenitis, non-hodgkin lymphoma and metastatic squamous cell carcinomas.

Conclusions: Thus Fine needle aspiration cytology of lymph nodes as a first line of investigation is a cost-effective procedure and is not only useful in the diagnosis of various lesions but can also help in deciding on appropriate management.

Keywords: Fine needle aspiration cytology, Tuberculous lymphadenitis, Metastatic tumors, Lymphoma.

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Corresponding Author

Dr Neha Mukesh Goel

204/5, Nai Sarak, Shastri Nagar, Meerut, U.P-250001

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