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Category: Volume 06 Issue 06 June 2018
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Title: Hepatitis B Virus Burden in Jammu (J&K): A Maiden Study

Authors: Dr Shashi S Sharma, Dr Konika Razdan, Mamta Sharma, Sonali Sharma, Sourabh S Sambyal

 DOI:  https://dx.doi.org/10.18535/jmscr/v6i6.106

Abstract

Background: Sero-surveillance of Hepatitis B virus infection in the Jammu province of J and K, India.

Objectives: The study was envisaged with the objective to (1) Study the Hepatitis B burden in the Jammu province (2) To further formulate the regional management policy, study the Genotypes and conduct Phylogenetic analysis based on this study.

Methods: Referred patient’s blood specimens were collected for HBsAg ELISA and tested. The test results were shared with both patients and the clinicians. 

Results: The prospective study was conducted from January 2014 to December 2016 wherein a total of 27,703 ELISA tests were performed and 678 patients were positive (2.44%). Male (64.60%) preponderance was observed over females (35.39%) with an overall positivity of 1.58% and 0.86% respectively. Highest prevalence of 54.71% was observed in the age group of 41-60 years followed by a prevalence of 29.20% in 19 to 40 years, 14.45% in 61-80 and 1.44% in the age group above 80. Of the 27,703 samples screened 449 (1.62%) were from the HIV-ART clinic and 7(1.55%) were found to be co-infected.

Conclusion: A seroprevalence of 2.44% was reported with male predominance (58.35%) with the maximum number of affected population being in the age group of 41-60 years (54.71%). The co prevalence of HBsAg and HIV was found to be 1.55%.

Keywords: Hepatitis B virus, HBsAg ELISA, seroprevalence, preponderance, co- infection.

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Corresponding Author

Dr Shashi S Sharma

Prof, PI and Nodal Officer

VRDL Dept. of Microbiology, GMC Jammu, India

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