Title: Cutaneous Manifestations of Diabetes Mellitus

Authors: Narendar Gajula, Raj Pratheepa, Vontela Rohit, Nishita Vumma

 DOI:  https://dx.doi.org/10.18535/jmscr/v6i6.90

Abstract

Background: Diabetes Mellitus is a common medical disorder presents with spectrum of cutaneous manifestation and up to 1/3rd of patients with Diabetes Mellitus were found to have cutaneous changes. Diabetes mellitus affects individuals of all ages and socioeconomic status. Skin manifestations are common during 5th decade of life.

Aim: To Study clinical pattern of various dermatological conditions in Diabetes Mellitus observed in Patients who attended our tertiary care centre in Karimnagar district.

Material and Method: A Total of 100 Diabetes Mellitus Patients with cutaneous manifestations attended our tertiary care Centre, Karimnagar were randomly selected in this study.

Results: Total 100 cases results were analyzed, and the Analysis shows cutaneous manifestations have slightly more predilection for Male gender (62%). Among the cutaneous Manifestation, Infections are the most common manifestation which constitute (61%). In infections, fungal infection is the most common infection. Among the fungal infection Dermatophyte constitute (59%) followed by candidal infection (41%). Second most common Manifestation is due to metabolic disorders like acanthosis  Nigricans,  acrochordon. The least common Manifestation is specific cutaneous markers like bullosis diabeticorum, granuloma annulare and necrobiosislipoidica.

Conclusion: Diabetes patients are susceptible to cutaneous lesions which are uncommon in non-diabetes. Any patient presents with recurrent and multiple cutaneous manifestations need to be checked for diabetes immediately. The ignorance of such manifestation or improper treatment makes the condition worse and leads to complications.

Keywords: Diabetes Mellitus, Cutaneous Manifestation.

References

  1. Wild S, Roglic G, Green A, Sicree R, King H; Global prevalence of diabetes, estimates for the year 2000 and projection for 2030. Diabetes Care, 2004; 27:1047-1053.
  2. Sicree R, Shaw J, Zimmet P; Diabetes and impaired glucose tolerance. In: Gan D, editor. Diabetes atlas. International diabetes federation. 3rd ed. Belgium: International Diabetes Federation, 2006; 15-103.
  3. Ronald GB, Ricky KS. The skin and Diabetes Mellitus, Int J Dermatol, 1984;23:567-584.
  4. Abhishek goyal, Sujeet Raina, Satinder S kaushal, Vikram Mahajan , Nand Lal Sharma Indian Journal of Dermatology. Patterns of cutaneous manifestations in diabetes mellitus. 2010 Jan-Mar; 39–41.John D. Bancroft, Alan Stevens, Theory and Practice of histological techniques; 2nd edition; 95- 122.
  5. P. Satyanarayana Rao1 . Dr.V. Srilakshmi2 , Dr. Ch.Kishore Kumar 3 , Dr.R. Vijaya Bhaskar4 . 1 (Associate Professor, Depatment Of Pathology, Rangaraya Medical College, Kakinada, Andhra Pradesh, India),jan2017.
  6. Shahzad M, Robaee AA, Shobaili HAA, Alzolibani AA, Marshood AAA, Moteri BA: Skin manifestations in diabetic patients attending a diabetic clinic in the Qassum region, Saudi Arabia. Med Princ Pract 2011;20:137-41.
  7. Raghunatha S, Anitha B, Inamdar AC, Palit A, Devarmani SS. Cutaneous disorders in 500 diabetic patients attending diabetic clinic. Indian J Dermatol 2011;56:160-4.
  8. Manjunatha M1 , Dadapeer HJ 2 , Darshan S3 1Associate Professor, 2 Professor and HOD, 3 Interns, Department of Dermatology, Venereology and Leprology, Shimoga Institute of Medical Sciences, Shimoga, Karnataka, India,2016.
  9. Romano G, Moretti G, Di Benedetto A, Giofre C, Di Cesare E, Russo G, et at. Skin lesions in diabetes mellitus: prevalence and clinical correlations. Diabetes Res Clin Pract 1998;39:101-6.
  10. Tanjore Y Raghu, V Vinayak, Garehatti kanthraj; Cutaneous manifestation of diabetes mellitus: Indian journal of dermatology, 2004; 49(2):73-75
  11. Nigam PK, Pande S. Pattern of dermatoses in diabetics. Indian J Dermatol Venereol Leprol 2003;69:83-5.
  12. Bhat R, Khaitan BK. Skin manifestations in internal diseases. In: Valia RG, Valia AR, editors. IADVL textbook of dermatology. 3rd Mumbai: Bhalani publishing house; 2010. p. 1347-409.
  13. Goyal A, Raina S, Kaushal SS, Sharma NL. Pattern of cutaneous manifestations in diabetes mellitus. Indian J Dermatol Venereol Leprol 2010;55:39-41.
  14. Timshina DK, Thappa DIABETES MELLITUS, Agarwal A. A clinical study of dermatoses in diabetes to establish its markers. Indian J Dermatol 2012;57:20-5.
  15. Thappa DIABETES MELLITUS. Skin tags as markers of diabetes mellitus: An epidemiological study in India. J Dermatol 1995;22:729-31.  
  16. Farshchian M, Farshchian M, Fereydoonnejad M, Yazdapfar A, Kimyai-Asadi A. Cutaneous manifestations of diabetes mellitus: A case series. Cutis 2010;86:31-5.
  17. Mahajan S, Koranne RV, Sharma SK. Cutaneous manifestations of diabetes mellitus. Indian J Dermatol Venereol Leprol 2003;69:105-8.
  18. AI- Mutairi N, Zaki A, Sharma AK» Sheltawi MA. Cutaneous manifestations of diabetes mellitus. Med Princ Pract 2006;15:427-30.

Corresponding Author

Dr Narendar Gajula

Associate Professor, Department of Dermatology, Venerology and Leprosy,

Chalmeda Anand Rao Institute of Medical Sciences, Bommakal – 505001, Karimnagar District, Telengana State, India

Telephone Number: 09704565018, Email: This email address is being protected from spambots. You need JavaScript enabled to view it.