Title: Unusual association of leptomeningitis, pachymeningitis, dural sinus thrombosis, posterior uveitis and pathergy in alady with Behcet’s disease
Authors: Varghese V B, Kamalasanan C.G, Shiji P.V, Kiran Kamalasanan
DOI: https://dx.doi.org/10.18535/jmscr/v6i6.89
Abstract
Behcet’s disease is an autoimmune disease characterised by recurrent orogenital ulcers and neurological disease, ocular disease, thrombosis, arthritis etc. Classically diagnosed using pathergy test even though a majority of the cases do not exhibit the same. In routine clinical practice the International criteria for Behcet’s developed by the International study group for Behcet’s is used. Despite the diversity in presentations in Behcet’s, it is rare to see multiple systemic manifestations in a single patient. Here we present a case with Behcet’s meningitis, dural sinus thrombosis, posterior uveitis, recurrent orogenital ulcers and a positive pathergy test all of which are cardinal features of Behcet’s that make 6 out of all 7 features considered in the International criteria.
Keywords: Behcet’s disease, leptomeningitis, pachymeningitis, dural sinus thrombosis, pathergy test
References
- Behcet’s Disease: A 32-year-old female with recurrent ocular inflammation. [Internet]. [cited 2018 Apr 12]. Available from: https://webeye.ophth.uiowa.edu/eyeforum/cases/195-Behcets.htm
- Davatchi F. Behcet’s disease. Int J Rheum Dis. 2014 May;17(4):355–7.
- Mat MC, Sevim A, Fresko I, Tüzün Y. Behçet’s disease as a systemic disease. Clin Dermatol. 2014 Jun;32(3):435–42.
- Noel N, Drier A, Wechsler B, Piette J-C, De Paz R, Dormont D, et al. [Neurological manifestations of Behçet’s disease]. Rev Med Interne. 2014 Feb;35(2):112–20.
- Rokutanda R, Kishimoto M, Okada M. Update on the diagnosis and management of Behçet’s disease. Open Access Rheumatol Res Rev. 2015;7:1–8.
- Dalvi SR, Yildirim R, Yazici Y. Behcet’s Syndrome. Drugs. 2012 Dec 3;72(17): 2223–41.