Title: Antibody positive Myasthenia Gravis associated with Chiari type I malformation and Thymoma
Authors: Remya P.V, Kamalasanan.C.G, Kiran Kamalasanan, Aquil Kalanad
DOI: https://dx.doi.org/10.18535/jmscr/v6i6.20
Abstract
Myasthenia Gravis is an autoimmune disease that affects neuromuscular junction. It usually presents with weakness of proximal muscles and has predilection for extraocular and bulbar muscles. Chiari I malformation can sometimes mimicsero negative myasthenia gravis. But here we present a case with an unusual association with both Chiari malformation and antibody positive myasthenia gravis occurring in the same patient. The patient also had cervical spondylosis and thymoma. Myasthenia gravis was serologically proven and Magnetic resonance imaging confirmed syringomyelia and ectopic cerebellar tonsils. Such an association has not so far been reported in literature.
Keywords: Myasthenia gravis, Chiari malformation, Syringomyelia.
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