Title: A Prospective and Observational Immunological Correlation Analysis of Non Classical with Classical Clinical Spectrum of Dengue Disease at Tertiary Health Centre

Authors: Dr N.Uma, Dr Shivam Yadav

 DOI:  https://dx.doi.org/10.18535/jmscr/v6i5.146

Abstract

Introduction

Dengue is a mosquito borne viral disease caused by Dengue virus (DEN-1, 2, 3&4). Dengue is endemic in more than 100 countries[1]. Dengue constitutes a major cause of pediatric morbidity and mortality in South East Asian countries[2]. Dengue fever (DF) has been reported from India over a longtime, but dengue hemorrhagic fever (DHF) was first reported in 1963 from Calcutta city[3]. Since then several outbreaks of dengue fever have been reported from India with a major epidemic of dengue hemorrhagic fever that occurred in Delhi in 1996 when 10,252cases and 423 deaths were reported[3]. Manifestation in children and adults differ in many ways. In a study, children had higher proportion of DHF I (42.9%) cases, whereas 51% adults were of DHF II. Some clinical manifestations, such as petechiae, melena, headache, retro-orbital pain, joint pain, myalgia, nausea and vomiting were more common in adult patients[8]. This study was undertaken to evaluate clinical profile and outcome of adult admitted with DHF/Dengue Shock Syndrome (DSS), dengue like illnesses amongst the adult admitted ii ABG Hospital Delhi from 2017.

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Corresponding Author

Dr Shivam Yadav

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