Title: Study of Various Perforation Peritonitis: On Tobacco User and Non-Tobacco User

Authors: Santosh More, Sanjay Jain

 DOI:  https://dx.doi.org/10.18535/jmscr/v6i5.63

Abstract

Background: Perforation peritonitis with effect of tobacco delays the healing of gastric duodenal ulcer and increases the risk of peptic ulcer is one of the commonest surgical emergencies encountered by surgeons all over the world. The aim of this study is to examine and compare the case of perforation peritonitis and found the relationship of tobacco with that of peptic perforation.

Material and Method: This clinicopathological study was examined 250 patient of perforation peritonitis. Who were admitted in ward of the department of surgery in Gandhi Medical College and, associated Hamidia Hospital Bhopal (M.P.) from August 2010 to November 2011.

Results: Out of total 250 patients 142 gastric perforation and 108 was intestinal perforation. Out of 142 gastric perforations patient 120 were tobacco user, while only 37 patients were tobacco user out of 108 patient of the intestinal perforation. Patients with perforation peritonitis were mostly in age group of 40-49 years. Postoperative complications were significantly higher in gastric perforation with tobacco use as compared to cases with intestinal perforation with tobacco use. Postoperative complication is significantly higher in the patient who used tobacco in both from smoking and chewing in compare to single from among perforation. Average day of hospital stay were significantly higher in patient of gastric perforation (13.94 days) with tobacco use as compared to intestinal perforation (18.4 days) with tobacco use. Average day of hospital stay were significantly more in cases with tobacco user (11.19 days) as compared to non-user (8.1 days).

Conclusion: Our study shows that gastric perforation is more common in tobacco user group in comparison to non-tobacco user and intestinal perforation group.

Keyword: Perforation; Peritonitis; Gastric; Intestinal; Tobacco.

References

  1. Balamaddiah G, Ravindranath G G. Etiology and complications of perforated peritonitis: a retrospective study. IntSurg J. 2018;5(3):908-912
  2. Ersumo T, Kotisso B. Perforated peptic ulcer in TikurAnbessa Hospital: a review of 74 cases. Ethiopian Med J. 2005; 43(1):9-13.
  3. Jhobta RS, Attri AK, Kaushik R, Sharma R, Jhobta A. Spectrum of perforation peritonitis in India-review of 504 consecutive cases. World Journal of Emergency Surgery. 2006; 1:26.
  4. Bali RS, Sharma AK, Soni RK. Etiology and management of perforation peritonitis: perspective from developing world. IntSurg J. 2017;4(9):3097-3100
  5. Eastwood GL. The role of smoking in peptic ulcer disease. J ClinGastroenterol. 1988;10 Suppl 1:S19-23
  6. Ordonez CA, Puyana JC. Management of Peritonitis in the Critically Ill Patient. The Surgical clinics of North America. 2006; 86(6):1323-1349.
  7. Balmiki P, Garg N, Nalge B. Spectrum of Perforation peritonitis in Bhopal with specialreference to NSAID induced GI perforations. J. Dent. Medi. Scie. 2015; 14(3): 102-105.
  8. Mishra SS, Kale LM, Sodhi SJ, Mishra PS, Mishra AS. Prevalence of oral premalignant lesions and conditions in patients with tobacco and tobacco-related habits reporting to a dental institution in Aurangabad . J Indian Acad Oral Med Radiol 2014;26:152-7
  9. Svanes C, Soreide J, Skarstein A, et al. Smoking and ulcer perforation. Gut. 1997; 41(2):177-180.
  10. Nannini LD, Leo D. An analysis of acute perforated peptic ulcer. Permonente Foundation Medical Bulletin. 1944; 1:1-11.
  11. Lee FY, Leung KI. Predicting mortality and morbidity of patients operated on for perforated peptic ulcers. Arch Surg. 2001; 136(1):90-4.
  12. Tonnessen T, Carlsen E. Perforated ulcer. Tidsskr Nor Laegeforen. 2001; 121(7):790-2.
  13. Jain NK, Jain MG, Maini S, Khobragade V. A study of clinical profile and management of perforation peritonitis in a tertiary health centre located in Central India. IntSurg J. 2017; 4:981-7.
  14. Crofts TJ, Park KG, Steels RJ. A randomized trial of non-operative treatment for perforated peptic ulcer. N Engl J Med. 1989; 320(15):970-3.
  15. Mock CN, Amaral J, Visser LE. Improvement in survival from typhoid ileal perforation results of 221 operative cases. Ann Surg. 1992; 215(3):244-9.
  16. Eduaro E, Montalvo-Jave EE, Corres-Sillas O, Athie-Gutierrez Factors associated with postoperative complications and mortality in perforated peptic ulcer. Cir Cir. 2011; 79(2):141-8.
  17. F Smedley, T Hickish, M Taube,CYale,R Leach, C Wastell. Perforated Duodenal Ulcer and Cigarette Smoking. J. Roy. Soci. of Medi.1988;81(2): 92-94.
  18. Oheneh-Yeboah M. Postoperative complications after surgery for Typoid Ilealperformation in adults in Kumasi. West African J Med. 2007; 26(1):32-6.

Corresponding Author

Dr Santosh More

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