Title: Assessment of Risk Factors Associated with Coronary Artery Diseases in a Study Population- A Clinical Study
Authors: Rajesh Khare, Sorabh Gupta
DOI: https://dx.doi.org/10.18535/jmscr/v6i4.151
Abstract
Background: Coronary artery disease (CAD) is one of the most common causes of mortality and morbidity in general population in both developed and developing countries. It is a leading cause of death in India. The present study was conducted to assess the risk factors for CAD.
Materials & Methods: The present study was conducted on 120 patients of both genders. Blood pressure measurement was carried out in each subject. Body weight (Kg) and height (m) were measured. Body mass index (BMI), defined as weight/ height (kg/ m2) was also calculated. Complete blood count, fasting plasma glucose (FPG), post-prandial plasma glucose (PPPG), lipid profile was calculated.
Results: out of 120 patients, males were 75 and females were 45. The difference was significant (P-0.01). Height (m) in males was 164.2±4 and in females was 150.4±2. Weight (kg) in males was 72.5±5 and in females was 64.4±2. BMI was 25.2±3 in males and 26.7±3 in females. SBP was 130.4±12 in males and 124.2±4 in females. DBP was 92.2±6 in males and 86.6±2 in females. FPG was 95.2±2 in males and 93.2±8 in females. PPPF was 136.4±1 in males and 129.5±2 in females. Total cholesterol was 188.0±12 in males and 185.1±12 in females. HDL was 44.2±2 in males and 48.7±3 in females. The difference was significant (P< 0.05).Family history was seen in 5% males and 4.2% females, smoking in 14% in males and 8% in females, DM in 17% in males and 10% in females, hypertension in 24% in males and 13% in females, dyslipidemia in 52% in males and 32% in females, BMI> 30 in 7% males and 16.50% females. The difference was significant (P < 0.05).
Conclusion: CAD is a commonly occuring disease having high mortality and morbidity. Contributing factors includes diabetes, obesity, hypertension etc.
Keywords: Coronary artery disease, Diabetes, Obesity.
References
- Goel PK, Bharti BB, Pandey CM, et al. A tertiary care hospital-based study of conventional risk factors including lipid profile in provencoronary artery disease. Indian Heart J 2003;55:234–40.
- Pais P, Pogue J, Gerstein H, et al. Risk factors for acute myocardial infarction in Indians: A case–control study. Lancet 1996;348:358–63.
- Gopalan S, Shiva M. National profile on women, health and development: India. New Delhi: Voluntary Health Association of India, 1999.
- Ramanakumar AV. Reviewing disease burden among rural Indianwomen. Online J Health Allied Sci 2004;2:1.
- Singh RB, Ghosh S, Niaz MA, et al. Epidemiologic study of diet andcoronary risk factors in relation to central obesity and insulin levels in therural and urban populations of north India. Int J Cardiol 1995;47:245–55.
- Shekhri M, Ganguly KN. Premature coronary artery disease inIndians and its associated risk factors. Vasc Health Risk Manag2005;1:217–25.
- Ramachandran A, Snehalatha C, Latha E, et al. Clustering of cardiovascular risk factors in urban Asian Indians. Diabetes Care1998;21:967–71.
- Siwach SB, Singh H, Sharma D, Katiyal VK. Profile ofyoung acute myocardial infarction in Haryana. JAPI1998; 46: 424-6.
- Dwivedi et al. Coronary Artery Disease in the Young: Heredofamilial or Faulty Life Style or Both. Journal, Indian Academy of Clinical Medicine 2000; 1: 222-29.