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Category: Volume 06 Issue 04 April 2018
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Title: Study showing the assessment with correlation of 25-hydroxy Vitamin D and HbA1c in type 2 Diabetes Mellitus

Authors: Dr Garima Sehgal, Dr Tejinder Singh

 DOI:  https://dx.doi.org/10.18535/jmscr/v6i4.146

Abstract

Background: Vitamin D deficiency reportedly is associated with type 2 diabetes (T2DM). We aim to examine whether 25-hydroxyvitamin D (25OHD) has clinically significant influence on hemoglobin glycation (HbA1c) in T2DM subjects.

Aim: To assess the serum levels of 25-Hydroxy Vitamin D and HbA1c as well as to study the correlation of these parameters in Known Patients of type 2 Diabetes Mellitus.

Material and Methods: This hospital-based study was conducted on 45 diagnosed type 2  Diabetes mellitus  patients  and 25  non-diabetic age and gender matched controls .Blood sample were  collected in plain vial as well as EDTA vial and serum 25-hydroxy vitamin D levels and HbA1c  were evaluated. Results were collected and analyses statically. 

Results: Vitamin D deficiency was seen in 35.6% and 32.6% of T2DM cases and control subjects respectively. There was no association of serum 25OHD deficiency on HbA1c in Type 2 Diabetes Mellitus patients with r value of -0.171 and -0.237 in study and control group respectively.

Conclusion: Our findings suggests that though vitamin D deficiency is prevalent in T2DM and non-diabetic subjects, its role in hemoglobin glycation could not be established.

Keywords: Diabetes, Vitamin D, HbA1c.

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Corresponding Author

Dr Tejinder Singh

Department of Biochemistry, Government Medical College, Amritsar