Title: Histopathological Study of Endometrial & Corpus Luteum Disparity

Authors: Patidar Ekta, Nandedkar S, Malukani K

 DOI:  https://dx.doi.org/10.18535/jmscr/v6i4.119

Abstract

The  human corpus luteum, a temporary endocrine gland derived from the ovulated follicle, is a major source of steroid hormones, producing up to 40 mg of progesterone per day.(1)  It is abruptly formed from the remnants of the preovulatory follicle, and it undergoes continuous change  and studied as early, middle, and late luteal phases in ovulatory cycle.(2) The pattern of progesterone production throughout the luteal phase determines menstrual cyclicity & endometrial receptivity for successful implantation , and is essential for maintenance of early pregnancy.(1) The breach in the mechanism leads to endometrial & corpus luteal  disparity.

Keywords: Endometrium; Corpus luteum; Progesterone.

References

  1. evoto L, Fuentes A, Kohn P, Cespedes P,Palamino A,Pommer A. The human corpus luteum: life cycle and function in natural cycles. Fertility and Sterility. September 2009 ;92(3):1067-79.
  2. Gibson M .Corpus Luteum. Glob. libr. women’s med. , ISSN :1756-2228)2008; DOI 10.3843/GLOWM.10291.
  3. Creatsas M, Creastas G.Dysfunctional Uterine Bleeding during adolesecence. Frontiers in Gynecological Endocrinology .DOI 10.1007/-3-319-03494-2_2.  
  4. Perez R.J, Plurad A.V, Palladino V.S .The relationship of the corpus luteum & the endometrium in infertile patients. Fertil Steril 1981;35 :423 -427 .
  5. Miller P, Soules M. Glob. libr. women's med., Luteal Phase Deficiency: Pathophysiology, Diagnosis, and Treatment (ISSN: 1756-2228) 2009; DOI 10.3843/GLOWM.10327.
  6. Lutjen P, Trounson A, Leeton J, Findlay J, Wood C, Renou P. The establishment and maintenance of pregnancy using in vitro fertilization and embryo donation in a patient with primary ovarian failure. Nature .1984; 307:174-76.
  7. Santoro N, Laura T, Goldsmith, Heller D, Illsley N, McGovern P et al. Luteal progesterone relates to histological endometrial maturation in fertile women. The Journal of Clinical Endocrinology and metabolism. November 2000; 85 (11):4207-4211. DOI: 10.1210/jc.85.11.4207

Corresponding Author

Patidar Ekta

Email: This email address is being protected from spambots. You need JavaScript enabled to view it.