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Category: Volume 06 Issue 04 April 2018
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Title: Study on the Demographical Profile of Chronic Obstructive Pulmonary Disease in Central India, New Delhi

Authors: Dr Ved Prakash Ghilley (MD, Medicine), Dr D. P. Bhadoria (MD, Medicine) , Dr Sanjay Pandit (MD, Medicine)

 DOI:  https://dx.doi.org/10.18535/jmscr/v6i4.110

Abstract

Background: The Global Initiative for Chronic Obstructive Lung Disease (GOLD) defines chronic obstructive pulmonary disease (COPD) as “a disease state characterized by airflow limitation that is not fully reversible. Due to progressive airflow limitation, the patients become increasingly symptomatic leading to worsening in their health-related quality of life (HRQOL). Therefore we undertook the present study is to examine associations between COPD and four measures of HRQOL using Saint George Respiratory Questionnaire (SJRQ) in hospital-based COPD patients without co-morbid conditions.

Method

Sample: One hundred twenty consecutive stable COPD patients (diagnosed as per GOLD guidelines) , >40 years of age, without any co-morbid conditions (diabetes, congestive heart failure, coronary artery disease, hypertension) were recruited in this study after intuitional ethical clearance and informed consents. A proper history and demographic details and routine clinical examination were recorded.

Tools: The health-related quality of life (HRQOL) was assessed using Hindi SGRQ-C. Forced expiratory volume in first one second (FEV1), forced vital capacity (FVC) and FEV1/FVC% and reversibility were measured using Spirolab III (Medical International Research USA, Inc.).

Statistical analysis: The descriptive analysis was done in the data treatment with the SPSS version 20.

Result: The mean age of the COPD patients was (mean±SD) 53.38±8.0 (range 45-83) years. Most of the patients (93.30%) were current or past heavy smokers. Most of these patients were concentrated in GOLD stage 3(36.7%) and stage 4(40.8%). Age, BMI, pack years and GOLD staging were not significantly associated with HRQOL.

Conclusion: Indian patients with COPD show significantly reduced HRQOL as measured by disease specific questionnaire SGRQ, similar to COPD patients in other countries. In our study, only FEV1 % predicted was significantly correlated with HRQOL, all other measures including GOLD staging were not significantly associated with HRQOL

Keyword: pulmonary obstructive.

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Corresponding Author

Dr Ved Prakash Ghilley (M.D. Medicine)

Assistant Professor, Late Lakhiram Agrawal memorial Govt. Medical College,

Associated Kirodimal Govt. Hospital, Raigarh, CG, India