Title: Ketamine- The wonder drug in Status Asthmaticus

Authors: Dr Gayatri Sakrikar, Dr Rachana Chhabria, Dr Anish Dave

 DOI:  https://dx.doi.org/10.18535/jmscr/v6i4.90

Abstract

A 20 year old male was admitted to intensive care unit with status asthmaticus. Conventional bronchodilator therapy as well as mechanical ventilation failed to improve his lung dynamics. A trial of inj. Ketamine as bolus of 1mg/kg followed by infusion of 1mg/kg was given. There was improvement in the lung dynamics with decreased peak airway pressures and PaCO2. Patient was weaned and extubated on the fifth day of admission. This case report emphasizes that Ketamine can be a useful drug in life threating severe asthma.

References

  1. Chung KF, Wenzel SE, Brozek JL, Bush A, Castro M, Sterk PJ, et al. International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma. Eur Respir J. 2014;43(2):343–73.
  2. FARHAD HESHMATI, et al. Use of Ketamine in Severe Status Asthmaticus in Intensive Care Unit. Iranian Journal of Allergy, Asthma and Immunology, [S.l.], p. 175-180, Dec. 2003. ISSN 1735-5249.
  3. Goyal S, Agrawal A. Ketamine in status asthmaticus: A review. Indian Journal of Critical Care Medicine: Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine. 2013; 17(3):154-161. doi:10.4103/0972-5229.117048.
  4. Townley RG. Beta-Adrenergic Receptors and Mechanisms in Asthma: The New Long-Acting Beta-Agonists. Allergol Int [Internet]. 1996;45(1):13–22.

Corresponding Author

Dr Gayatri Sakrikar

Department of Anaesthesiology, Seth G S Medical College and KEM Hospital, Mumbai