Title: Comparative Study of Insulin Resistance in Healthy young Adults with and without Family History of Diabetes Mellitus
Authors: Dr Sharana Basappa, Dr Ravikumar Ryakha, Dr Nilanjan Sengupta, Dr Pranab Kumar Sahana, Dr Arjun Baidya, Dr Soumik Goswami, Dr Sattik Siddanta, Dr Sreenath R
DOI: https://dx.doi.org/10.18535/jmscr/v6i4.83
Abstract
Family history of diabetes is an important risk factor for diabetes mellitus. Insulin resistance (IR) is central feature in the natural history of Impaired glucose tolerance (IGT) and Type-2 DM. we studied occurrence of insulin resistance in healthy young adults and subjects with family history of diabetes. Subjects with F/H of DM had higher levels of fasting plasma insulin and Insulin Resistance compared to those without F/H of DM Recognition of IR in the pre-disease state would be beneficial, as it affords, potential implementation of interventions designed to reduce such disease development.
Keywords: Insulin Resistance; Metabolic syndrome; FPI; HOMA_IR; Diabetes mellitus.
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