Title: Assessment of Lipid profile in relation to antiretroviral therapy in HIV Population in Western Maharashtra

Authors: Dadasaheb G. Maindad, B.Palange, R.Bhagwat

 DOI:  https://dx.doi.org/10.18535/jmscr/v6i4.39

Abstract

There were several studies done for the prevalence and pattern of dyslipidaemia in HIV patient but most of them were conducted in urban setting and there was no study done from western HIV population in India in rural set up to show the lipid profile in HIV patient.

Keeping in view of this, the biochemical abnormalities associated with lipid metabolism, our research was inclined to assess the lipid profile in HIV patients. This study will also add our knowledge that whether the lipid profile has any role in the disease progression of HIV AIDS.

Keywords: Lipid profile ART, HIV, dyslipidemia, biochemical abnormalities.

References

  1. Grunfeld C, Kotler DP, Hamadeh R, Tierney A, Wang J, Pierson RN. Hypertriglyceridemia in the acquired immunodeficiency syndrome. Am J Med. 1989;86:27–31.
  2. Boccara F. Cardiovascular complications and atherosclerotic manifestations in the HIV-infected population: type, incidence and associated risk factors. AIDS. 2008;3:S19–26.
  3. Mehta N, Reilly M. Atherosclerotic cardiovascular disease risk in the HAART-treated HIV-1 population. Clin Trials. 2005;6:5–24.
  4. Hoffmann C, Jaeger H. Cardiology and AIDS - HAART and the consequences. Ann N Y Acad Sci. 2001;946:130–44.
  5. Leonard EG, McComsey GA. Metabolic complications of antiretroviral therapy in children. Pediatr Infect Dis J. 2003;22:77–84.
  6. Floridia M, Tamburrini E, Ravizza M, Tibaldi C, Ravagni Probizer MF, Anzidei G, et al. Lipid profile during pregnancy in HIV-infected women. HIV Clin Trials. 2006;7:184–93.
  7. Kramer AS, Lazzarotto AR, Sprinz E, Manfroi WC. Metabolic abnormalities, antiretroviral therapy and cardiovascular disease in elderly patients with HIV. Arq Bras Cardiol. 2009;93:561–8.
  8. Dronda F. Cardiovascular risk in patients with chronic HIV-1 infection: a controversy with therapeutic, clinical and prognostic implications. Enferm Infecc Microbiol Clin. 2004;22:40–5.
  9. Lipid profile of HIV-infected patients in relation to antiretroviral therapy: a review_ Suelen Jorge Souzaa, Liania Alves Luziaa, Sigrid Sousa Santosb, Patrícia Helen Carvalho Rondóa., Rudo Muswe, Olav Oktedalen, Danai T. Zhou, Enita Zinyand, Sandra Shawarira-Bote, Babill Stray-Pedersen, Atipa Siziba and Zvenyika A.R. Gomo, Inflammatory Markers and Plasma Lipids in HIV Patients: A Correlation Analysis Study.
  10. Grunfeld C1, Kotler DP, Hamadeh R, Tierney A, Wang J, Pierson RN Hypertriglyceridemia in the acquired immunodeficiency syndrome. Am J Med. 1989 Jan;86(1):27-31.
  11. Edwards-Jackson, N.; Kerr, S.; Tieu, H.; Ananworanich, J.; Hammer, S.; Ruxrungtham, K.; Phanuphak, P.; Avihingsanon, A. Cardiovascular risk assessment in persons with HIV infection in the developing world: Comparing three risk equations in a cohort of HIV-infected Thais. HIV Med., 2011, 12(8), 510-515.
  12. Nisar A. Wafai, Khwaja Saifullah Zafar*, Manoj Kumar, Prem S. Singh, Sudhir K. Yadav, Pattern of dyslipidaemia in human,immunodeficiency virus infected patients- a study from rural,tertiary care hospital in central India, , International Journal of Research in Medical Sciences ,Wafai NA et al. Int J Res Med Sci. 2016 Oct;4(10):4349-4355
  13. Hattab, S.; Guihot, A.; Guiguet, M.; Fourati, S.; Carcelain, G.; Caby, F.; Marcelin, A-G.; Autran, B.; Costagliola, D.; Katlama, C. Comparative impact of antiretroviral drugs on markers of inflammation and immune activation during the first two years of effective therapy for HIV-1 infection: An observational study. BMC Infect. Dis., 2014, 14, 122.
  14. Saurabh G. Sadekar and S. N. Bentoor/ International Journal of Biomedical and Advance Research 2016; 7(3): 128-130.
  15. Assessment of lipid profile in patients with human immunodeficiency virus (HIV/ AIDS) without antiretroviral therapy Arun Kumar, Brajesh Sathian

Corresponding Author

Gayatri Gawade Maindad

Assistant Professor, Dept. of Biochemistry, BVDUMC, Pune, India

Email: This email address is being protected from spambots. You need JavaScript enabled to view it., Mobile No: 9326739058