Title: Incidence of Hodgkin’s & Non Hodgkin’s Lymphomas and Comparison of Their Hematological Parameters
Authors: Mustafa Ali, Fatima Bhopalwala Ali
DOI: https://dx.doi.org/10.18535/jmscr/v6i4.37
Abstract
Background: There is a rise in incidence of lymphomas over the past few years. They can arise in lymph nodes, other lymphatic tissues and extranodal organs. Changes in complete blood count frequently occur lymphomas.
Objective: To look for incidence of various lymphoma and abnormal hematological parameters associated with lymphomas
Material and Methods: We performed complete blood count and peripheral blood examination on all the FNAC or biopsy proven cases of Hodgkin’s (HL) & Non Hodgkin’s lymphoma (NHL) visiting Department of Pathology, King George’s medical university after taking proper history, consent and general examination.
Results: Diffuse large B Cell lymphoma was most common subtype in NHL while in HL mixed cellularity type was most commonly encountered. The Hb level was towards lower side in both the group but was higher among the patients of Hodgkin’s Lymphoma compared with Non Hodgkin’s group. However there was no significant difference in total leukocyte count and platelet count between Hodgkin’s lymphoma and Non Hodgkin’s Lymphoma. Peripheral blood examinations revealed majority of Red blood cells were normocytic normochromic.
Conclusion: Majority of the patient had anaemia and leucocytosis and peripheral blood involvement in form of abnormal lymphoid cell was present in 5 cases out of 40 (12.5%) without any other significant hematological manifestations.
Keywords: Hodgkin’s lymphoma, Non Hodgkin’s lymphoma, Complete blood count, peripheral blood examination
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