Title: Seroprevalence of Transfusion Transmitted Infections among Blood Donors in a Tertiary Care Hospital in Madhya Pradesh
Authors: Ramole Archana, Pawde Yogesh
DOI: https://dx.doi.org/10.18535/jmscr/v6i4.08
Abstract
Background: Blood transfusion is a life-saving procedure. However, the recipient has the potential risk of acquiring transfusion-transmissible infections (TTI), important infectious agents being Human Immunodeficiency Virus (HIV), Hepatitis B & C viruses, and Treponema pallidum.
AIM: This study was undertaken to know the prevalence of TTI in our hospital blood bank and hence evaluate the safety of the blood units.
Material and Method: The present study was conducted at the Blood Bank of Gandhi Medical College, Hamidia Hospital, Bhopal. Data was collected retrospectively for a 8-9 years period from January 2007 to December 2016. Donor data including demographic details and results of the screening tests were recorded.
Results: In the 8-9 years period, there were 1,37, 156 donors - both voluntary and replacement donors. The donors were in the age group of 18 to 60 years. Out of the 3453 donors tested positive for any test, there were 19 female donors and the 3434 male donors. The donors who tested positive formed 2.5% of the total number of donors. The maximum, number of donor were positive for HBsAg (n=2990), followed by positivity for HCV (n=306) and HIV) n=157). The seroprevalence of HBsAg. HCV, HIV and Syphilis was 2.17, 0.22, 0.11, 0.02% and 0.62% respectively. There was no case with smear positive for malaria parasite.
Conclusion: The seroprevalence of TTI is minimal in our set up. The risk can be kept to a minimum by proper donor selection and testing of the collected units.
Keywords: HIV, Hepatitis B virus, Hepatitis C virus, Blood donors.
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