Title: Platelet disorders is common cause of bleeding manifestation pediatrics age group –study at tertiary heath care center CNBC & M.Y. Hospital Indore
Authors: Dr Shailendra Singh Thakur, Dr C.V. Kulkarni
DOI: https://dx.doi.org/10.18535/jmscr/v6i4.04
Abstract
Objectives & Aims: 1) To determine the hematological findings & coagulation profile of the study subjects. 2) To find out relevant clinical findings of study subjects through clinical examination & detail history. 3) To find the correlation of the clinical findings with the hematological findings studied. To establish probable diagnosis in the study subjects. To find the incidence of spectrum of diseases in bleeding disorders. To find the age and sex distribution of the cases studied.
Material & Methods: Blood was collected in a sterile EDTA containing tube and processed following our established hospital based laboratory protocol. A complete blood counting including HB%, PCV, Red cell indices, platelet count, total white cell count done by Automated blood cell counter. The all cell count indices including RBC, WBC count with differential along with morphological changes further confirmed by manual oil immersion smear study method. Peripheral smears study was done with field A and B stain and leishman stain.
Conclusion: This In our study we found that in most of the cases of thrombocytopenia i.e below 1,50000 count (81%), automated counter give very low platelet counts while on peripheral smear examination, the count is not that much reduced but different morphological variations of platelets like megathrombocytes, platelet aggregates and platelet fragments are found. These variations denote inactive or non functional platelets, hence despite of the low normal or near normal platelet counts , patient present with bleeding.
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