Title: Validation of endometrial curettage and histopathological examination in abnormal uterine bleeding: An tertiary centre study

Authors: Dr Aksharaditya Shukla, Dr Ashok Panchonia, Prof. Dr C V Kulkarni, Dr Poorva Agarwal

 DOI:  https://dx.doi.org/10.18535/jmscr/v6i3.220

Abstract

Abnormal uterine bleeding (AUB) is common gynecological problem and is of serious concern in developing countries as it adds to the causes of anemia. It includes bleeding which could be with or without any organic cause. It is termed as dysfunctional uterine bleeding (DUB) when there are no demonstrable pelvic or systemic diseases and no anatomical lesion. AUB may be the common presenting complaint in patients with pre-malignant or malignant endometrial lesion. Clinically AUB present as menorrhagia, metrorrhagia or polymenorrhagia. Of various modalities present for AUB diagnosis, dilation & curettage is most effective as it provide a definitive diagnosis and many a times curative also. We studied 210 females, in duration of two years who undergone D&C for evaluation of AUB. Their clinico radiological findings, drug history etc were noted and findings were co-related with histopathological findings. Mean age of presentation was 39.6 years. Reproductive age group and multipara were more commonly affected. Menorrhagia was most common clinical presentation followed by metrorrhagia and polymenorrhagia. Endometrial hyperplasia was most common cause followed by proliferative endometrium (24.28%), pregnancy complication, chronic endometritis and others. Conclusion: AUB is common gynecological problem of reproductive age group. Proper evaluation of AUB is necessary as it is common problem in reproductive age, increases the prevalence of anemia and may represent to underlying malignancies.

Keywords: Abnormal Uterine bleeding (AUB), Dysfunctional Uterine Bleeding (DUB), Menorrhagia, Metrorrhagia..

References

  1. Nicholson WK, Ellison SA, Grason H, Power NR. Patterns of ambulatory care use for gynecological conditions: a national study. Am J Obstect Gynecol 2001;184.
  2. Munro MG, Critchley HO, Fraser IS. The FIGO classification of causes of abnormal uterine bleeding in the reproductive years. Fertil Steril 2011;95:2204-8.
  3. Fraser IS, McCarron G, Markham R et al. Blood and total fluid content of menstrual discharge. Obstet Gynecol.1985; 65:194–8.
  4. Albers JR, Hull SK, Wesley MA. Abnormal uterine bleeding. Am Fam Phys 2004;69:1915-26.
  5. Dallenbach, Hellwig G. Functional disturbances of endometrium. Chapter-11. Haines & Taylor Obstetrical & Gynecological Pathology. Edt.By Fox H, 4th edition, Churchill Levinstone, 1995;383-403.
  6. Montgomery BE, Daum GS. Endometrial Hyperplasia: a review. Obstet Gynecol Surv 2004;59:368-78.
  7. Long C.A. Evaluation of patients with abnormal uterine bleeding. AM-J-obstect gynecol 1996;seo. 175(3 pt 2):784-6.
  8. Neese RE Abnormal vaginal bleeding in perimenopausal women. Am Fam physician 1989:0:185.
  9. Johnson CA. Making sense of dysfunctional uterine bleeding. Am Fam physician 1991;14:149-57.
  10. Samson, SL, Donna G. Who needs an endometrial biopsy? Canadian Family Physician 2002;48:885.
  11. John W Ely, Collen M, Kennedy, et al. Abnormal uterine bleeding: A Management Alogrithm. Midwest Centre for health Services and Policy research 2007;105(11): 624-30{4p}.
  12. Sarwar A, Haque A. Types and frequency of pathologies in endometrial curetting of abnormal uterine bleeding. Int J Pathol 2005;3:65-70.
  13. Sarwat A, Roohi M, Histological diagnosis by conventional dilatation and curettage.Professional Med J Oct-Dec 2011;18(4):587-591
  14. Saraswathi D, Thanka J. Study of endometrial pathology in Abnormal Uterine Bleeding. The journel of Obstetrics and Gynecology of India (July-aug 2011) 61(4):426-430.
  15. Patil R, Patil RK, Andola SK, Laheru V, Bhandar M. Histopathological spectrum of endometrium in dysfunctional uterine bleeding. Int J Bio Med Res. 2013;4(1):2798-2801.
  16. Pilli GS et al. Dysfunctional uterine bleeding-A study of 100 cases. J Obstet Gynecol India. 2000;52{3}:87-89.
  17. Mehrotra VG et al. Functional uterine bleeding-A review of 150 cases. J Obstet Gynecol India.1972;12:684-689.

Corresponding Author

Dr Ashok Panchonia

Associate Professor, Department of Pathology,

Mahatma Gandhi Memorial Medical College, Indore, MP India