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Category: Volume 06 Issue 03 March 2018
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Title: Study of Clinico-pathological Spectrum of Lymphadenopathy

Authors: Saini Sunita, Mathur Kusum, Sharma Priyanka, Pankaj JP, Yadav Ajay

 DOI:  https://dx.doi.org/10.18535/jmscr/v6i3.164

Abstract

Introduction: Inflammation or enlargement of lymph nodes has clinical significance because it occurs in various diseases ranges from throat infections to life threatening cancers. The lymph node involvement has an important role in cancer staging which decides treatment and prognosis. So, present study was planned to know incidence of various causes of lymphadenopathy by the histopathological examination and to find out association with age and gender.

Materials and Methods: A cross sectionalstudy was carried out in Department of Pathology, SMS Medical College, Jaipur (Rajasthan) from June 2016 to June 2017. Total 110 cases of lymphadenopathies were included and analyzed by histopathological examination of Hematoxylin and Eosin stained sections.

Results: Benign enlargement is the most common cause of lymphadenopathy. 3rd and 4th decade of life were commonly affected age groups with M:F ratio 1.44:1. More than half cases were of cervical lymphadenopathies. Non-neoplastic lymphadenopathy was mostly due to tuberculosis while neoplastic lymphadenopathy was due to metastatic deposits.

Conclusion: Although lymphadenopathy is mostly related with benign lesions but it necessitates a careful physical examination and follow up of patient and care should be taken in malignancy. Excisional biopsy can be used as the gold standard in the diagnosis of lymphadenopathy.

Keywords: Lymphadenopathy, Benign, Malignant, Histopathology.

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Corresponding Author

Mathur Kusum

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