Title: Endoscopıc Fındıngs in Dıabetıc Patıents wıth Dyspepsıa in Al-Ramady General Hospıtal

Author: Dr Hafed I Hussein (MD)

 DOI:  https://dx.doi.org/10.18535/jmscr/v6i3.144

Abstract

Objectives: To understand the occurrence of dyspepsia in patients with diabetes mellitus. Also to understand symptoms overlapped from both diseases.

Patients and Methods: A total of 56 diabetic patients; 19 (34%) type I, and 37 (66%)  type II were considered in this study according to the comparative clinical features of types I and II.

Results: Type I diabetes mellitus patients are found to be more likely to contract esophagitis and gastritis, gastric stasis and pre-pyloric ulcer.  On the other hand type II diabetes mellitus patients are found to be more likely to contract cancer of the stomach, multiple esophageal ulcer, pyloric ulcer, antral gastritis and duodenal ulcer and gastro-duodenitis.

Conclusion: Patients with diabetes mellitus duration of less than 10 years are more likely to contract esophagitis and gastritis, duodenitis, gastric stasis and multiple esophageal ulcers, while patients with diabetes mellitus duration more than 10 years are found to be more likely to contract pyloric ulcer and antral gastritis and duodenal ulcer.

Keywords: Diabetes mellitus DM; Dyspepsia; Endoscopic findings.

References

  1. Kenneth R. MCQuaid, Dyspepsia, Gastrointestinal and Liver disease.  In: Sleisnger and FORTRAN’s, Chapter 7, 7th Edition, Volume 1, 2002.
  2. Locke R III (1998).  Prevalence incidence and nature history of dyspepsia and functional dyspepsia.  Ballever U.N. Gastroentrol (12):435.
  3. Tack J, Talley NJ, Camilleri M, et al. Functional gastroduodenal disorders. Gastroenterology. 2006;130:1466–79.
  4. Wild S, Roglic G, Green A, Sicree R, King H. Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diab Care. 2004;27:1047–53.
  5. Haquem, Wyeth J, Stace N. et al. (2000).  Prevalence, severity and associated features of gastro esophageal reflux and dyspepsia.  A population based study.  NZ Med J (1130):178.
  6. Frier, B.M. and Fisher, B.M. Diabetes mellitus: Major manifestations of disease. In Davidson’s Principle and Practice of Medicine.  19th edt., Churchill-Livingstone, Toronto, 2002, page 950.
  7. Jean D. Wilson. Principles of endocrinology. In Harrison’s principles of internal medicine 2. 11th edt., McGraw-Hill Book Company, New York, 1987, page 1790.
  8. Locke, G.R (1995). Epidemiology of gastrointestinal complications of diabetes mellitus.
  9. Barkin JS, Robbins EG, Stein B. Diabetes and the GI system. In: Ellenberg and Rifkin’s editors. Diabetes Mellitus. 5th edt., Lange; 1997, 1183-93.
  10. Djaj apranata I. Gastro paresis in: Symposium diabetic gastro paresis. Ujung Pandang; (1995).
  11. Krahulec B. Azaazim, Vozair Retal.  Diabetick Al Polyneuropatica, Barbis lava, lufema (1999), 73-88.
  12. Marton DG, Whorwell PJ (1991).  Functional bowel symptoms in diabetes, the role of autonomic neuropathy.  Postgrad. Med. J; 67:991-993.
  13. Mearin F, Malageluda JR. (1995).  Gastro paresis and dyspepsia in patients with diabetes mellitus.  Europ J Gastroenteral Hepatol; 7:717-723.
  14. S1 Frim D. Janssens J. Vantrappen G.  (1996).  Transient lower esophageal sphincter and esophageal body muscular contractive response in normal humans.  Gastroenterology; 110:659-668.
  15. Armstrong D (1999).  Endoscopic evaluation gastro esophageal reflux disease.  J Biol Med (72):93-100.
  16. Magdy El-Salhy (2004). Overview of Diabetic Gastroenteropathy. Geriatric Times.
  17. Pradana S. (1999). Gastroparesis in diabetes: When to suspect? Disampaikan Pada Jakarta Diabetes Mellitus Meeting, 19-20 November 1999.
  18. Nasrul Zubir (2003).  Endoscopic diagnosis of upper gastrointestinal tract, motility disorder at M. Djamil Hospital Padang.
  19. Osipenko MF, Zhuk EA, Medvedeva OV.  Diabetes mellitus and dyspepsia syndrome.  Klin Med (Mosk). 2008;86(10):13-6.
  20. Osipenko MF, Zhuk EA, Medvedeva OV.  Clinical characteristics of dyspepsia in patients with diabetes mellitus type 2.  Ter Arkh. 2013;85(2):43-7.
  21. Antwi ch, Krahulec  B,Michalkol, Strboval, Hinstakova S,Balazovjech I,(2003). Does Diabetic autonomic neuropathy influence the clinical manifestatiom of reflux esophagitis? Bratisl Lek Listy; 104 (4 –5); 139 – 42.
  1. Dordaneh Maleki, MD; G. Richard Locke III, Michael Camilleri, MD; Alan R. Zinsmeister, PhD; Barbara P. Yawn; Cynthia Leibson, PhD; L. Joseph Melton III, MD (2000). Gastrointestinal tract symptoms among persons with diabetes mellitus in the community. Arch Interm Med; 160:2808-2816.

Corresponding Author

Dr Hafed I Hussein (MD)

Ramadi Teaching Hospital, Internal Medicine Dept,

AL-Anbar Health Directorate, Iraq