Title: A Prospective Study to Compare the Outcome of Intralesional Triamcinolone Alone and Intralesional Triamcinolone with 5 Fluro-Uracil Combination in Cases of Hypertrophic Scar and Keloid
Authors: Dr Yogesh Kailasia, Dr Shambhu Dayal Barua, Dr Priyank Sharma, Dr APS Gaharawar, Dr Mohit Gangwal
DOI: https://dx.doi.org/10.18535/jmscr/v6i3.12
Abstract
Objective: A prospective study to compare the outcome of Intralesional triamcinolone alone and intralesional triamcinolone with 5 fluro-uracil combination in cases of hypertrophic scar and keloid.
Material and Methods: The present study was carried in Department of general surgery S.S. Medical College and Associated S.G.M. Hospital, Rewa (M.P.) Total 66 study patients were included in present study. The studied patients were selected from Surgical O.P.D and I.PD during the period from June 2016 to May 2017.
Depending upon the size, site, duration of lesion, age and sex of the patient, the lesion were treated by intralesional triamcinolone alone and intralesional and 5 fluro-uracil combination in cases of hypertrophic scar and keloids”. Patients will be categorized into 2 groups:
Group A: Patients with hypertrophic scar and keloid treated with intralesional triamcinolone.
Group B: Patients with hypertrophic scar and keloid treated with intralesional triamcinolone+ 5-fluorouracil.
Evaluation of results for all the 66 patients will be done on the basis of visual inspection and by comparing serial photography.
Results: The 66 subjects in the study were divided into two equal groups of 33(50%) each. Good to excellent results were seen in 18(54.54%) cases in Group A compared to 27(81.81%) in Group B.
Conclusion: A combination regime of intralesional triamcinolone with 5-fluorouracil, found that the combination regime has better results than intralesional triamcinolone alone , in treatment of keloids and hypertrophic scars.
Keywords: 5-Fluorouracil, Hypertrophic scar, Keloid.
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