Title: Study of Hypercellular and Hypocellular smears in bone marrow aspiration at tertiary care centre M.Y. Hospital Indore
Authors: Dr Meena Mittal, Dr Rakesh Mehar, Dr Harshul Patidar, Prof. Dr C.V. Kulkarni
DOI: https://dx.doi.org/10.18535/jmscr/v6i2.204
Abstract
Background: Bone marrow aspiration is important investigation of haematological disorders not being clearly diagnosed on peripheral blood examination.
Objective: The present study was done to find out prevalence of etiological diagnosis in hypercellular and hypocellular bone marrow aspirates.
Material and Methods: The present study was conducted in the Department of Pathology, M.G.M. Medical College Indore, from January 2017 to February 2018. Total 38 cases were studied. The diagnosis in all the cases were made on Field stained and Leishman stained slides of bone marrow aspirates.
Results: Among the 38 cases, 26.3% shows Megaloblastic anemia, 7.9% shows Aplastic Anemia, 15.7% shows Hypoplastic Bone marrow, 2.6% shows Erythroid hyperplasia, 5.3% shows Immune Thrombocytopenic Purpura, 7.9% shows Myeloproliferative disorder, 5.3% shows Myelodysplastic syndrome, 5.3% shows Acute Lymphoblastic Leukemia, 13.2% shows Acute Myeloid Leukemia, 2.6% shows Chronic myeloid leukemia, 5.3% shows NHL spillage, 2.6% shows Metastatic deposits. Among all cases 20 were males and 18 were females.
Conclusion: Bone marrow aspiration is easy and cheap investigation in evaluation of haematological and non-haematological disorders of bone marrow. Majority of bone marrow aspirates were hypercellular, among which common finds were Megaloblastic anemia and acute leukemia.
Keywords: Bone marrow aspiration, Megaloblastic anemia, Acute leukemia.
References
- Taj Ali Khan et al. Diagnostic role of bone marrow aspiration and trephine biopsy in haematological practice. J Postgrad Med Inst 2014; 28(2):217-21.
- Swapna Kumari B et al., J. App. Med. Sci., Apr 2017; 5(4E):1598-1605
- Damulak OD, Damen JG. Diagnostic outcome of bone marrow aspiration in a new centre in Nigeria. GloAdv Res J Med Sci 2012;1(7):166-171.
- Bashawri LA. Bonemarrow examination Indications and diagnostic value. Saudi Med J 2002 Feb; 23(2):191-196.
- Melina Desalphine et al. Journal of Clinical and Diagnostic Research. 2014 Nov, Vol-8(11): FC11-FC15
- Manjit Kaur et al., Journal of Clinical and Diagnostic Research. 2014 Aug, Vol-8(8): FC13-FC16.