Title: To Study the Association of Retinopathy with Plasmodium Species in Children’s with Cerebral Malaria

Authors: Dr Puneet Agrawal, Dr Jyoti Singh, Dr Sujata Lakhtakia

 DOI:  https://dx.doi.org/10.18535/jmscr/v6i2.173

Abstract

Objectives: To study the association of retinopathy with plasmodium species in children’s with cerebral malaria

Design: Prospective, observational, cohort study. Cohort study comprising of all malaria positive patients.

Setting: Study was carried out in Department of Paediatrics, S.S.M.C and associated G.M. Hospital Rewa, Madhya Pradesh during the period of 1st August 2015 to 31st July 2016.

Participants: 100 consecutive patients with cerebral malaria evaluated by ophthalmologist for changes of retinopathy were included in the study. All 100 cases were malaria positive.

Results: In cerebral malaria out of 100 cases, 12 cases were Plasmodium vivax positive, 74 cases are Plasmodium falciparum positive, and 14 cases are both Plasmodium vivax and Plasmodium falciparum positive. Out of total 41 cases of retinopathy maximum cases were Plasmodium falciparum positive (78%), Plasmodium vivax is positive in 2.5% of cases. While 19.5% cases were both pv and pf positive.

Conclusions: Malarial retinopathy is significantly associated with P.falciparum species of malarial parasite in children with cerebral malaria indicating P.falciparum as the most important cause of cerebral malaria or serious disease.

Keywords: Cerebral Malaria, Retinopathy, Plasmodium vivax, Plasmodium falciparum.

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Corresponding Author

Dr Puneet Agrawal

Room no.8, PG Boys Hostel, S.S. Medical College, Rewa (M.P.), Pin – 486001 INDIA

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