Title: Clinicopathological Study of Hashimoto’s Thyroiditis and Its Management
Authors: Dr Amarendra Prasad N, Dr Akhilesh Reddy Thumma, Dr Ashwini Dutt Awaru
DOI: https://dx.doi.org/10.18535/jmscr/v6i2.115
Abstract
Hashimoto’s thyroiditis is a common cause of goitrous enlargement with hypothyroidism. This study was done to study various clinical presentations with thyroid function and to diagnose and treat the cases with thyroxine and how many cases needed surgical procedure.
Patients presenting to surgical outpatient with goitrous enlargement were subjected to hormonal assay and FNAC. If FNAC showed features of lymphocytic infiltration they were subjected to autoantibody titers. All the patients with Hashimoto’s thyroiditis were put on thyroxine and regular follow-up was done to note the clinical signs and symptoms including the size of the goiter. Patients with obstructive symptoms or goiter in whom size did not reduce or for cosmetic reasons were operated.
Hashimoto’s thyroiditis was more in females and maximum in 30-40 years of age group. Out of 50 cases with the history from 1 month to 3 years, 62% were multinodular goiter, 36% were diffuse goiter and 2% was solitary nodule. Regarding thyroid function 54% were hypothyroid, 34% were Euthyroid and 12% were hyperthyroid. FNAC showed Hashimoto’s thyroiditis in about 47 patients out of 50 cases studied. Antibody titers were positive for 92 of cases, 3 cases were operated out of which 1 case had obstructive symptoms.
Keywords: Hashimoto’s thyroiditis, Multinodular Goitre, FNAC, Autoantibody titers.
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