Title: Study of Baseline Titres for Widal test among Population in Kakinada Region of AP.
Authors: Dr CH. Aruna Kumari, Dr K. Rajasekhar, Dr K.R.L Surya Kirani, Dr D. Satyanarayana Murthy
DOI: https://dx.doi.org/10.18535/jmscr/v6i2.107
Abstract
Background: Culture is the gold standard for diagnosis of enteric fever. Due to the poor isolations of Salmonella in recent times, Widal test is still a useful alternative aid. Good interpretation of the test cannot be made unless we know the correct baseline titres in population of particular area.
Aim and Objectives: To determine the base line titres of antibodies in healthy individuals.
Material and Methods: Blood samples were collected from 100 healthy individuals from August to November 2017. Widal tube agglutination test was performed to know the titres.
Results: In the total samples screened, most frequently recorded titre for O & H agglutinins were 1:40 for Salmonella Typhi. Similarly for Salmonella Paratyphi A and B, anti H titres were 1:20 each respectively.
Conclusion: It is concluded that the cut-off value of antibodies titres for Salmonella Typhi O and H antigens is >1:40, and for Paratyphi A & B H antigen is >1:20 in this region. Any titre more than this should be taken as high and interpreted in correlation with clinical findings or titers observed in paired sera.
Keywords: Baseline titre, Widal tube agglutination test, Enteric fever, Healthy population.
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