Title: Service User’s Attitudes and Experiences Regarding Substitution Therapy with Buprenorphine

Authors: Dr Rohit Garg, Dr Khushbinder Singh, Dr Kriti Anand, Dr Balwant Singh Sidhu, Dr Purushottam Dass Garg

 DOI:  https://dx.doi.org/10.18535/jmscr/v6i2.58

Abstract

Introduction: No Indian study has explored attitudes and experiences of patients towards buprenorphine. The present study was done to assess the experiences and attitudes of buprenorphine users towards the drug.

Material and Methods: 200adult males from opioid substitution therapy centers were cross-sectionally assessed. After taking written informed consent, socio-demographic and clinical performa, Attitudes towards Buprenorphine Questionnaire (translated in Punjabi) were applied. Appropriate statistical methods were used.

Results: Mean age of participants was 34.44 ± 10.113 years. Majority had less than 12 years of formal education (68%), were married (55.5%) and resided in joint families (69.5%) in urban locality (76%). Mean Attitudes towards buprenorphine questionnaire score was 100.69 ± 16.304. Mean dose of buprenorphine was 6.38 ± 3.252 mg/day. More than 90% patients agreed that buprenorphine reduced craving, provides a normal life to an ex-addict and had done good for patients. However, 80% expressed that it should be stopped as early as possible. Nearly 40% believed that buprenorphine was an addiction, gives a high and difficult to stop. 80% patients endorsed that daily visits were problematic.

Conclusions: There is a huge gap between the number of patients who might benefit from buprenorphine and those who receive it. The positive attitudes and experiences of patients taking buprenorphine can be effectively used to bring out of treatment opioid addicts in the treatment system. Novel and diverse ways to deliver buprenorphine to suit the needs of majority of patient population are the need of the hour.

Keywords: Attitudes, Buprenorphine, Experiences, Opioid substitution therapy.

References

  1. Petersen Z, Myers B, van Hout MC, Pluddemann A, Parry C. Availability of HIV prevention and treatment services for people who inject drugs: finding from 21 countries. Harm Reduct J 2013; 10:13. doi:  10.1186/1477-7517-10-13
  2. Rao R, Agrawal A, Ambekar A. Opioid Substitution Therapy under National Aids Control Programme: Clinical Practice Guidelines for Treatment with Buprenorphine. Department of AIDS Control, Ministry of Health and Family Welfare, Government of India, New Delhi: Government of India; 2014.
  3. Kumar MS, Natale RD, Langkham B, Sharma C, Kabi R, Mortimore G.Opioid substitution treatment with sublingual buprenorphine in Manipur and Nagaland in Northeast India: what has been established needs to be continued and expanded. Harm Reduct J 2009 6:4. doi: 10.1186/1477-7517-6-4.
  4. Kermode M, Armstrong G, Waribam S. Long-term follow up of clients from a community-based opioid substitution therapy programme in Manipur. Ind J Med Res 2011; 134 (5):732 - 4.
  5. Reid G, Sharma M, Higgs P. The Long Winding Road of Opioid Substitution Therapy Implementation in South-East Asia: Challenges to Scale Up. J Public Health Res 2014; 3 (1): 204. doi: 10.4081/jphr.2014.204.
  6. Schwartz RP, Kelly SM, O’Grady KE, Mitchell SG, Peterson JA, Reisinger HS, et al. Attitudes toward buprenorphine and methadone among opioid-dependent individuals. Am J Addict 2008; 17 (5): 396 - 401.
  7. Liu Y, Li L, Zhang Y, Zhang L, Shen W, Xu H, et al. Assessment of attitudes towards methadone maintenance treatment between heroin users at a compulsory detoxification centre and methadone maintenance clinic in Ningbo, China. Subst Abuse Treat Prev Policy 2013 8:29. doi: 10.1186/1747-597X-8-29.
  8. Kelly SM, Brown BS, Katz EC, O’Grady KE, Mitchell SG, King S, et al. A Comparison of Attitudes Toward Opioid Agonist Treatment among Short-Term Buprenorphine Patients. Am J Drug Alcohol Abuse 2012; 38 (3):233 - 8.
  9. Egan JE, Netherland J, Gass J, Finkelstein R, Wiess L, BHIVES collaborative. Patient perspectives on buprenorphine/naloxone treatment in the context of HIV care. J Acquir Immune DeficSyndr 2011; 56 (1): S46–S53.
  10. Goulao J. Attitudes and Beliefs Regarding Opioid Maintenance Treatment in Portugal: A Survey to Physicians, Patients and Opioid Users. Acta Med Port 2013; 26 (5): 537 - 48.
  11. Prakash SBalhara Y. Perceptions Related to Pharmacological Treatment of Opioid Dependence Among Individuals Seeking Treatment at a Tertiary Care Center in Northern India: A Descriptive Study. Subst Use Misuse 2016; 51 (7): 861 - 9.
  12. Balhara YPS, Ranjan R, Dhawan A, Yadav D. Experiences from a Community Based Substance Use Treatment Centre in an Urban Resettlement Colony in India. J Addiction. 2014;2014:982028.  doi: 10.1155/2014/982028.
  13. Shah PA, Sohler NL, López C, Fox AD, Cunningham CO. Awareness of, experience with, and attitudes toward buprenorphine among opioid users visiting a New York City syringe exchange program. J Opioid Manag 2013; 9 (6): 407 - 13.
  14. Sohler N, Weiss L, Egan JE, Lopez CM, Favaro J, Cordero R, et al. Consumer Attitudes about Opioid Addition Treatment: A focus group study in New York City. J Opioid Manag. 2013; 9 (2): 111 - 9.
  15. Wu F, Peng CY, Jiang H, Zhang R, Zhao M, Li J, et al. Methadone maintenance treatment in China: perceived challenges from the perspectives of service providers and patients. J Public Health 2013; 35 (2): 206 - 12.
  16. Stancliff S, Myers JE, Steiner S, Drucker E.Beliefs about methadone in an inner-city methadone clinic.J Urban Health 2002; 79 (4): 571 - 8.
  17. Woo J, Bhalerao A, Bawor M, Bhatt M, Dennis B, Mouravska N, et al. “Don’t Judge a Book by Its Cover”: A Qualitative Study of Methadone Patients’ Experiences of Stigma. Subst Abuse 2017;11:1178221816685087. doi: 10.1177/1178221816685087.

Corresponding Author

Dr Rohit Garg

Assistant Professor, Dept of Psychiatry,

Govt. Medical College & Rajindra Hospital, Patiala, Punjab, India

Email: This email address is being protected from spambots. You need JavaScript enabled to view it., Mobile: 919888145477