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Category: Volume 06 Issue 01 January 2018
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Title: Clinical and Morphological Profile in Breast Carcinoma Patients in a Tertiary Care Hospital, SMS Medical College, Jaipur, Rajasthan

Authors: Ranjita Bansal, Ajay Yadav, Vivek Gupta, Kavita Goyal

 DOI:  https://dx.doi.org/10.18535/jmscr/v6i1.177

Abstract

Objectives: Breast cancer is the most common malignancy in females. Data on breast cancer profile of patients in Rajasthan is scant. Patients have different clinical and morphological presentation and each case require appropriate strategy for screening, diagnosis and treatment purpose.

This study is conducted to find out clinical stage at which the patients presented, to assess the clinicomorphological spectrum of breast cancer patients and to correlate histological grade (Richardson bloom score) with clinical stage of disease.

Method: This prospective study was carried out on 100 newly diagnosed cases of breast carcinoma. Every eligible surgical specimens of breast carcinoma received in department of pathology.

Results: Mean age of patients was found to be lower compared to western countries. Many of the patients were from rural background and patients often presented with longer duration of symptoms and advanced clinical stage. Left side was more frequently involved. The tumour was commonly of higher grade . The more advanced stages were associated with higher grade at time of diagnosis.

Conclusion: Breast cancer occurs in younger age females in India including Rajasthan. Considering the younger age of presentation and decreased affordability of patients, mammography might be a less effective screening test due to higher density of breast in young age, which decreases the sensitivity of mammography. Patients are mostly from rural background and present more frequently with advanced stage breast cancer. Most Patients presented with advanced stage of breast carcinoma. A statistically significant positive correlation was seen between Histological grade and clinical stage of breast cancer. Awareness campaigns, breast self-examination, improved access to diagnostic resources and health care are important measures that should be undertaken for early diagnosis particularly in rural areas.

Keywords: Breast Cancer-Clinical Profile-Stage-Grade-India.

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Corresponding Author

Ranjita Bansal