Title: Dry Eye and Corneal Sensitivity in Patients with Type 2 Diabetes Mellitus

Authors: Dr Annapurna Kumar, Dr Malhar Vyas

 DOI:  https://dx.doi.org/10.18535/jmscr/v6i1.154

Abstract

Background: Ocular surface disorders in diabetes mellitus have gained significant attention in recent years, as there is increased reporting of the association of dry eye and diminished corneal sensitivity in these patients. However there is a wide variation in the reported prevalence rates, and a detailed ocular surface evaluation is still not routinely performed for all diabetic patients. We decided to undertake this study to study the prevalence of dry eye and corneal sensitivity in patients with and without type 2 diabetes mellitus, and to look for evidence of any association of these two conditions with diabetic retinopathy

Materials and Methods: This was a cross sectional study undertaken in patients presenting to the ophthalmology outpatient department. Patients above the age of 40 years who did not have any condition other than type 2 diabetes mellitus that could influence dry eye an corneal sensitivity were taken up for the study. Specific evaluation included a history of symptoms related to dry eye using the 5-Item Dry Eye Questionnaire, and then tear film evaluation, tear film break up time, fluorescein and lissamine green staining and Schirmer I test and corneal sensitivity testing with a Cochet-Bonnet esthesiometer.

Results: The prevalence of dry eye among diabetics was 48.9% and diminished corneal sensitivity was 28.9% as compared to 5.6% for both among the non-diabetics. There was a significant association with age and duration of diabetes but not with retinopathy.

Conclusion: A detailed ocular surface evaluation is recommended for all patients with diabetes to detect early evidence of ocular surface disorders so that institution of appropriate management may be undertaken at the earliest.

Keywords: Dry eye, diabetes, corneal sensitivity, corneal sensation, retinopathy.

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Corresponding Author

Dr Annapurna Kumar

Department of Ophthalmology,

Sri Venkateshwaraa Medical College Hospital & Research Centre