Title: A Cross Sectional Study Showing Association of Serum Uric Acid in Pre-Diabetic and Diabetic Indian Population
Authors: Pushpalata Sachan, Dr R.S. Gangwar, Dr M.L. Patel, Dr M.M.Khan, Dr Indu Pisharody
DOI: https://dx.doi.org/10.18535/jmscr/v6i1.128
Abstract
Background: Diabetes is a huge burden worldwide and India is only second to China in prevalence of Diabetes. Recent studies showed that the prevalence of Diabetes and Pre-diabetes (IGT) is rapidly increasing, especially in urban population. Serum uric acid level varies in various stages of glucose homeostasis. The present study is coined to show the association of serum uric acid level with Diabetic and Pre-diabetic stage of glucose homeostasis.
Methods: This is a cross sectional observational study and enrolled total 79 subjects from medicine OPD during one year duration. On the basis of American Diabetic Association (ADA) guidelines 2010 among 79 subjects, 16 subjects were assigned as pre-diabetic and 63 as diabetic. Estimation of Serum uric acid was done by using MERK Kit with the help of semi-automated analyzer. The quantitative parametric datas were analysed by student “t” test whereas non parametric datas by Mann- whitney U test. The categorical datas were analysed by Chi square test.
Results: The Serum uric acid level in diabetic group was 5.79± 1.87 mg/dl (mean± SD) whereas in pre-diabetic group was 10.84± 2.84 mg/dl (mean± SD). So it is significantly lower in diabetics as compared to pre-diabetic. (p<0.001)
Conclusion: The present study suggests that that serum uric acid level is significantly higher in pre-diabetic group and may play a significant role in progression of Diabetes.
Keywords: Diabetes, Pre-diabetes, Serum Uric Acid.
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