Title: Histopathological Study of Tumors of Central Nervous System
Author: Jay Prakash
DOI: https://dx.doi.org/10.18535/jmscr/v6i1.71
Abstract
Background: A brain tumor occurs when abnormal cells from within the brain. There are two main types of tumors: malignant and benign tumors. This study was aimed to determine the types of brain tumor in study population.
Materials & Methods: This study was conducted in the department of general pathology on 112 specimens submitted to the department. The diagnosis was made on HPE of routinely processed tissue. The H&E stained sections in all cases were reviewed and diagnosis was confirmed applying revised WHO classification.
Results: Site distribution was cerebro parietal (35), cerebro frontal (25), cerebro temporal (8), cerebro occipital (5), cerebellum (10), pons (8), cerebellopontine angle (17) and spinal cord region (4). The difference was significant (P-0.01). Common CNS neoplasms were astrocytoma (33), meningioma (21), schwannoma (10), oligodendroglioma (12), medulloblastoma (6), neurofibroma (9), craniopharyngioma (5), ependymoma (6) and metastatic tumor (10). The difference was significant (P-0.01).
Conclusion: Astrocytoma was most common CNS neoplasm. Females had higher prevalence than males. Cerebro parietal region was commonly involved.
Keywords: Astrocytoma, Brain, Neoplasm.
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