Title: Comorbid Anxiety and Depression in Chronic Daily Head Ache Patients

Authors: Bhagyavathi Haralahalli Dalavayappa, Sumana Vasishta

 DOI:  https://dx.doi.org/10.18535/jmscr/v6i1.15

Abstract

Background: Patients with Chronic daily headache (CDH) have high frequencies of psychiatric comorbidities such as depression and anxiety which play a significant role in the development of drug resistance and chronicisation of primary headache. This study was done with the objectives of assessment of sociodemographic details and comorbid depression and anxiety in CDH patients.

Methodology: 200 patients diagnosed with CDH in the Department of Psychiatry were included in this cross-sectional study. The Hospital Anxiety and Depression Scale (HADS) was applied to assess anxiety and depression. Descriptive statistics and regression analyses were used.

Results: Majority of the patients were married middle age females. Migraine and TTH were present in 79.5% and 11.5% respectively. Among migraineurs, 37.1% patients had comorbid anxiety and depression. In those with TTH, 69.6% had anxiety and depressive symptoms. Migraine showed statistical significance (p<0.001) in multiple regression analysis.

Conclusion: In this study, a significant portion of the headache patients had comorbid anxiety and depression which calls for early intervention. It is thereby advised for the screening of mood and anxiety disorders in headache patients for a better prognosis and improvement in the quality of life.

References

  1. Giuseppe Nappi, Armando Perrotta, Paolo Rossi, and Giorgio Sandrini. Chronic daily headache. Expert Review Of Neurothera-peutics. 2008;8(3):361-384. 
  2. Halker R, Hastriter E, Dodick D. Chronic Daily Headache: An Evidence-Based and Systematic Approach to a Challenging Problem. Neurology. 2011;76;S37-S43.
  3. Singh A, Shukla R, Trivedi J, Singh D. Association of psychiatric co-morbidity and efficacy of treatment in chronic daily headache in Indian population. Journal of Neurosciences in Rural Practice. 2013;4 (2):132.
  4. Pompili M, Di Cosimo D, Innamorati M, Lester D, Tatarelli R, Martelletti P. Psychiatric comorbidity in patients with chronic daily headache and migraine: a selective overview including personality traits and suicide risk. The Journal of Headache and Pain. 2009;10(4):283-290.
  5. Guidetti V, Galli F. Psychiatric co-morbidity in chronic daily headache: Pathophysiology, etiology, and diagnosis.Curr Pain Headache Rep. 2002; 6:492–7.
  6. Gentili C, Panicucci P, Guazzelli M. Psychiatric comorbidity and chronicisation in primary headache. The Journal of Headache and Pain. 2005;6(4):338-340.
  7. Puca F, the Italian Collaborative Group. Psychological and social stressors and psychiatric comorbidity in patients with migraine without aura from headache centers in Italy a comparison with tension-type. The Journal of Headache Pain, 200; 1(1):17–25. doi:10.1007/ s101940050005
  8. Bera SC, Khandelwal SK, Sood M, Goyal V. A comparative study of psychiatric comorbidity, quality of life and disability in patients with migraine and tension type headache. Neurol India 2014;62:516-20
  9. Torelli, P., Lambru, G. & Manzoni, G.C. Psychiatric comorbidity and headache: clinical and therapeutical aspects. Neurol-igical Sciences. 2006;27(S2):s73-s76
  10. Silberstein SD, Lipton RB. Overview of diagnosis and treatment of migraine.  1994;44(10 S7):S6–16.
  11. Silberstein SD, Lipton RB. Chronic daily headache. Curr Opin Neurol. 2000; 13:277–83.
  12. Headache Classification Committee of the International Headache Society. The International Classification of Headache Disorders. (2nd ed) 2004; 24:9–160
  13. Zigmond, AS; Snaith, RP. "The hospital anxiety and depression scale".Acta Psychiatrica Scandinavica. 1983; 67 (6): 361–370.
  14. Snaith RP. The Hospital Anxiety And Depression Scale. Health and Quality of Life Outcomes. 2003;1:29. doi:10.1186/1477-7525-1-29.
  15. Ingvar Bjellanda, Alv A. Dahl, Tone Tangen Haug, Dag Neckelmann. The validity of the Hospital Anxiety and Depression Scale An updated literature review. Journal of Psychosomatic Research.2002 Feb; 52(2):69-77.
  16. Bhuvana RC. Prevalence of psychiatric co-morbidity in patients presenting with chronic daily headache: a hospital based cross sectional study. Int J Res Med Sci 2017;5:321-5.
  17. Jain AP, Mansur, Chauhan B, Bhat AD. Sociodemographic and Clinical Profile of Headache –A Rural hospital-based study. IACM. 2007;8(1):26-8
  18. Juang KD, Wang SJ, Fuh JL et al. Comorbidity of depressive and anxiety disorders in chronic daily headache and its subtypes. Headache 2000 Nov-Dec;40(10):818-23.
  19. Desai SD, Pandya RH. Study of psychiatric comorbidity in patients with headache using a short structured clinical interview in a rural neurology clinic in Western India. J Neurosci Rural Pract 2014;(5 S1):39-42
  20. Sivaji M, Manickavasagam J, Sundaram-urthi I, Gopinathan S. A study on prevalence and co-morbidity of bipolar and anxiety disorders in chronic headache patients. Int J Res Med Sci 2017;5:3038-43.
  21. Breslau N, Davis GC, Schultz LR, Peterson EL. Migraine and major depression, A longitudinal study. Headache. 1994;34(10):387-93.

Corresponding Author

Bhagyavathi Haralahalli Dalavayappa