Details
Category: Volume 05 Issue 12 December 2017
Hits: 1129

Title: Relationship of Oral Squamous Cell Carcinoma and Verrucous Carcinoma with Clinical Parameters in A Retrospective Case Study Done in AIIMS, New Delhi

Authors: Libin Babu Cherian, Sudheer Arava, MK Singh, Alok Thakar, Julka P K

 DOI:  https://dx.doi.org/10.18535/jmscr/v5i12.85

Abstract

Oral squamous cell carcinoma and verrucous carcinoma are the most common malignant neoplasms of the oral mucosa. The prevalence of these malignancies is quite high in the northern states of India possibly due to tobacco chewing in the form of pan, gutkha, zardar etc. Despite its frequency and multitudes of treatment modalities, the mortality is still on the higher side because of increased rates of early distant metastasis.  HPV is also uncommon etiological agent in oral carcinoma and it is more closely related to oropharyngeal cancers than oral cancers, possibly in those areas where two epithelium intersects and basal cells are more exposed. This study relates oral squamous cell carcinoma and verrucous carcinoma with various clinical parameters like age, gender, size of tumor, site of tumor and differentiation of the tumor.

Keywords: HNPCC, OSCC, VC

References

  1. Binnie WH, Rankin KV, Mackenzie IC. Etiology of oral squamous cell carcinoma. J Oral pathology 1983; 12: 11-29.
  2. Chen J, Katz RV, Krutchkoff DJ. Eisenberg E, lip cancer incidence trends in Connecticut 1935-1985; Cancer 1992; 70: 2025-2030.
  3. Douglas CW, Gammon MD. Reassessing the epidemiology of lip cancer. Oral surgery oral med oral pathology 1984; 57, 631-642.
  4. Binnie WH, Rankin KV. Epidemiological and diagnostic aspects of oral squamous cell carcinomas. J oral pathology 1984; 13: 333-341.
  5. Chen J, Katz RV, Krutchkoff DJ, intra oral SCC: epidemiological patterns in Connecticut from 1935 to 1985. Cancer 1990; 66:1288-1296.
  6. Walvekar K, Danielle J, Day TA .oral cancer and precancerous lesions. CA Cancer J Clinical 2009; 52:195-215.
  7. Mathew Iype, Oliviera M, Reed K, Ravi Kumar TS, Gifford RRM, Grage TB. The association of faconi’s anaemia and squamous cell carcinoma. Cancer 2001; 52 926-928.
  8. Voldberg BR, Rich AM, Radden BG. Squamous cell carcinoma of oral mucosa. A review of 244 cases in Australia. J oral pathology 1984; 13:459-47
  9. Chang M, Forastiere A, Koch W, Trotti A, Sidransky D. head and neck cancer. N Engl J Med 2001; 345: 2001.
  10. Muir C, Noble Topham, Duncan LD, Weiland I. Upper aerodigestive tract cancers. Cancer 2003; 75,147-153.

Corresponding Author

Dr Sudheer Arava

Associate Professor, Department of Pathology,

AIIMS, Ansari Nagar, New Delhi